Matches in SemOpenAlex for { <https://semopenalex.org/work/W1548248236> ?p ?o ?g. }
- W1548248236 endingPage "64" @default.
- W1548248236 startingPage "55" @default.
- W1548248236 abstract "In recent year's scientific and technological advancement have been made in the rate sustained oral drug delivery system by o overcoming physiological adversities, such as short gastric residence time (GRT) and unpredictable gastric emptying time (GET). So an interest increased towards novel dosage forms, that can retained in the stomach for a prolonged and predictable period of time. The concept of such novel dosage forms is to decrease the GI transit rate of the drug delivery system by attachment to the mucus layer, thereby increasing the overall time for drug absorption. This review presents a broad treatment of mucoadhesive nanoparticles discussing their advantages, limitations and their possible remedies. This review presents the most outstanding contributions in the field of gastro retentive mucoadhesive nanoparticles used as drug delivery systems. Methods of preparation, drug loading and drug release are covered. Mucoadhesive dosage forms may be designed to enable prolonged retention at the site of application, providing a sustained rate of drug release for improved therapeutic outcome. Application of dosage forms to mucosal surfaces may be of benefit to drug molecules not amenable to the oral route, such as those that undergo acid degradation or extensive first-pass metabolism. This review article aims to provide an overview of the various aspects of mucoadhesion, mucoadhesive approaches, factors affecting mucoadhesion, evaluating methods, and finally various mucoadhesive drug delivery systems (buccal, nasal, ocular, gastro, vaginal, and rectal)." @default.
- W1548248236 created "2016-06-24" @default.
- W1548248236 creator A5045445107 @default.
- W1548248236 creator A5061171955 @default.
- W1548248236 creator A5064522612 @default.
- W1548248236 date "2014-06-28" @default.
- W1548248236 modified "2023-09-27" @default.
- W1548248236 title "Gastro-retentive Mucoadhesive Nanoparticle for sustained drug delivery System" @default.
- W1548248236 cites W109788472 @default.
- W1548248236 cites W1526540441 @default.
- W1548248236 cites W1546060514 @default.
- W1548248236 cites W1599269431 @default.
- W1548248236 cites W1964355221 @default.
- W1548248236 cites W1972544495 @default.
- W1548248236 cites W1974558951 @default.
- W1548248236 cites W1976903082 @default.
- W1548248236 cites W1981968979 @default.
- W1548248236 cites W1986329432 @default.
- W1548248236 cites W1986367116 @default.
- W1548248236 cites W1994834911 @default.
- W1548248236 cites W1996998905 @default.
- W1548248236 cites W1997201109 @default.
- W1548248236 cites W1999768649 @default.
- W1548248236 cites W2003026662 @default.
- W1548248236 cites W2004173569 @default.
- W1548248236 cites W2010753465 @default.
- W1548248236 cites W2012756671 @default.
- W1548248236 cites W2012836594 @default.
- W1548248236 cites W2016449420 @default.
- W1548248236 cites W2018250782 @default.
- W1548248236 cites W2021013480 @default.
- W1548248236 cites W2024481699 @default.
- W1548248236 cites W2025182473 @default.
- W1548248236 cites W2030362379 @default.
- W1548248236 cites W2042132872 @default.
- W1548248236 cites W2047101587 @default.
- W1548248236 cites W2048478132 @default.
- W1548248236 cites W2050394185 @default.
- W1548248236 cites W2061053546 @default.
- W1548248236 cites W2068011156 @default.
- W1548248236 cites W2082599471 @default.
- W1548248236 cites W2087241994 @default.
- W1548248236 cites W2090593764 @default.
- W1548248236 cites W2091470606 @default.
- W1548248236 cites W2091992845 @default.
- W1548248236 cites W2094802034 @default.
- W1548248236 cites W2131041162 @default.
- W1548248236 cites W2135642567 @default.
- W1548248236 cites W2138281910 @default.
- W1548248236 cites W2141753050 @default.
- W1548248236 cites W2145322966 @default.
- W1548248236 cites W2147693421 @default.
- W1548248236 cites W2183415878 @default.
- W1548248236 cites W2186455044 @default.
- W1548248236 cites W2187692368 @default.
- W1548248236 cites W2290108652 @default.
- W1548248236 cites W2415983755 @default.
- W1548248236 cites W2505104219 @default.
- W1548248236 cites W2515910750 @default.
- W1548248236 cites W2523530498 @default.
- W1548248236 cites W2526490328 @default.
- W1548248236 cites W32040317 @default.
- W1548248236 cites W1875588174 @default.
- W1548248236 cites W2603725134 @default.
- W1548248236 hasPublicationYear "2014" @default.
- W1548248236 type Work @default.
- W1548248236 sameAs 1548248236 @default.
- W1548248236 citedByCount "0" @default.
- W1548248236 crossrefType "journal-article" @default.
- W1548248236 hasAuthorship W1548248236A5045445107 @default.
- W1548248236 hasAuthorship W1548248236A5061171955 @default.
- W1548248236 hasAuthorship W1548248236A5064522612 @default.
- W1548248236 hasConcept C13245373 @default.
- W1548248236 hasConcept C171250308 @default.
- W1548248236 hasConcept C192562407 @default.
- W1548248236 hasConcept C195735259 @default.
- W1548248236 hasConcept C2779820397 @default.
- W1548248236 hasConcept C2780020223 @default.
- W1548248236 hasConcept C2780035454 @default.
- W1548248236 hasConcept C71924100 @default.
- W1548248236 hasConcept C77281830 @default.
- W1548248236 hasConcept C98274493 @default.
- W1548248236 hasConceptScore W1548248236C13245373 @default.
- W1548248236 hasConceptScore W1548248236C171250308 @default.
- W1548248236 hasConceptScore W1548248236C192562407 @default.
- W1548248236 hasConceptScore W1548248236C195735259 @default.
- W1548248236 hasConceptScore W1548248236C2779820397 @default.
- W1548248236 hasConceptScore W1548248236C2780020223 @default.
- W1548248236 hasConceptScore W1548248236C2780035454 @default.
- W1548248236 hasConceptScore W1548248236C71924100 @default.
- W1548248236 hasConceptScore W1548248236C77281830 @default.
- W1548248236 hasConceptScore W1548248236C98274493 @default.
- W1548248236 hasIssue "2" @default.
- W1548248236 hasLocation W15482482361 @default.
- W1548248236 hasOpenAccess W1548248236 @default.
- W1548248236 hasPrimaryLocation W15482482361 @default.
- W1548248236 hasRelatedWork W1531264732 @default.
- W1548248236 hasRelatedWork W2020935675 @default.