FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1548352846> ?p ?o ?g. }

• W1548352846 abstract "Background This is an updated version of the original Cochrane review published in 2013, Issue 4. Low‐grade gliomas (LGG) constitute a class of slow‐growing primary brain neoplasms. Patients with clinically and radiographically suspected LGG have two initial surgical options, biopsy or resection. Biopsy can provide a histological diagnosis with minimal risk but does not offer a direct treatment. Resection may have additional benefits such as increasing survival and delaying recurrence, but is associated with a higher risk for surgical morbidity. There remains controversy about the role of biopsy versus resection and the relative clinical outcomes for the management of LGG. Objectives To assess the clinical effectiveness of biopsy compared to surgical resection in patients with a new lesion suspected to be a LGG. Search methods The following electronic databases were searched in 2012 for the first version of the review: Cochrane Central Register of Controlled Trials (CENTRAL) (2012, Issue 11), MEDLINE (1950 to November week 3 2012), Embase (1980 to Week 46 2012). For this updated version, the following electronic databases were searched: Cochrane Central Register of Controlled Trials (CENTRAL) (2016, Issue 5), MEDLINE (Nov 2012 to June week 3 2016), Embase (Nov 2012 to 2016 week 26). All relevant articles were identified on PubMed and by using the ’related articles’ feature. We also searched unpublished and grey literature including ISRCTN‐metaRegister of Controled Trials, Physicians Data Query and ClinicalTrials.gov for ongoing trials. Selection criteria We planned to include patients of any age with a suspected intracranial LGG receiving biopsy or resection within a randomized clinical trial (RCT) or controlled clinical trial (CCT). Patients with prior resections, radiation therapy, or chemotherapy for LGG were excluded. Outcome measures included overall survival (OS), progression‐free survival (PFS), functionally independent survival (FIS), adverse events, symptom control, and quality of life (QoL). Data collection and analysis A total of 1375 updated citations were searched and critically analyzed for relevance. This was undertaken independently by two review authors. The original electronic database searches yielded a total of 2764 citations. In total, 4139 citations have been critically analyzed for this updated review. Main results No new RCTs of biopsy or resection for LGG were identified. No additional ineligible non‐randomized studies (NRS) were included in this updated review. Twenty other ineligible studies were previously retrieved for further analysis despite not meeting the pre‐specified criteria. Ten studies were retrospective or were literature reviews. Three studies were prospective, however they were limited to tumor recurrence and volumetric analysis and extent of resection. One study was a population‐based parallel cohort in Norway, but not an RCT. Four studies were RCTs, however patients were randomized with respect to varying radiotherapy regimens to assess timing and dose of radiation. One RCT was on high‐grade gliomas (HGGs) and not LGG. Finally, one RCT evaluated diffusion tensor imaging (DTI)‐based neuro‐navigation for surgical resection. Authors' conclusions Since the last version of this review, no new studies have been identified for inclusion and currently there are no RCTs or CCTs available on which to base definitive clinical decisions. Therefore, physicians must approach each case individually and weigh the risks and benefits of each intervention until further evidence is available. Some retrospective studies and non‐randomized prospective studies do seem to suggest improved OS and seizure control correlating to higher extent of resection. Future research could focus on RCTs to determine outcomes benefits for biopsy versus resection." @default.
• W1548352846 created "2016-06-24" @default.
• W1548352846 creator A5016185028 @default.
• W1548352846 creator A5019253871 @default.
• W1548352846 creator A5021433932 @default.
• W1548352846 creator A5025858111 @default.
• W1548352846 creator A5031431944 @default.
• W1548352846 creator A5063689978 @default.
• W1548352846 date "2017-04-27" @default.
• W1548352846 modified "2023-09-26" @default.
• W1548352846 title "Biopsy versus resection for the management of low-grade gliomas" @default.
• W1548352846 cites W1266779413 @default.
• W1548352846 cites W1548352846 @default.
• W1548352846 cites W1569307548 @default.
• W1548352846 cites W1959628099 @default.
• W1548352846 cites W1964025236 @default.
• W1548352846 cites W1966992856 @default.
• W1548352846 cites W1968683066 @default.
• W1548352846 cites W2002291505 @default.
• W1548352846 cites W2003107243 @default.
• W1548352846 cites W2018464587 @default.
• W1548352846 cites W2028653658 @default.
• W1548352846 cites W2028827431 @default.
• W1548352846 cites W203981073 @default.
• W1548352846 cites W2051885387 @default.
• W1548352846 cites W2072044537 @default.
• W1548352846 cites W2075642745 @default.
• W1548352846 cites W2076566420 @default.
• W1548352846 cites W2083526222 @default.
• W1548352846 cites W2085510136 @default.
• W1548352846 cites W2090841741 @default.
• W1548352846 cites W2093579014 @default.
• W1548352846 cites W2094940716 @default.
• W1548352846 cites W2100242207 @default.
• W1548352846 cites W2100791391 @default.
• W1548352846 cites W2102628178 @default.
• W1548352846 cites W2107328434 @default.
• W1548352846 cites W2116232743 @default.
• W1548352846 cites W2116638587 @default.
• W1548352846 cites W2116693415 @default.
• W1548352846 cites W2117942958 @default.
• W1548352846 cites W2119838967 @default.
• W1548352846 cites W2124892137 @default.
• W1548352846 cites W2125435699 @default.
• W1548352846 cites W2132581465 @default.
• W1548352846 cites W2134942438 @default.
• W1548352846 cites W2140510570 @default.
• W1548352846 cites W2141570482 @default.
• W1548352846 cites W2144727376 @default.
• W1548352846 cites W2147865633 @default.
• W1548352846 cites W2162643152 @default.
• W1548352846 cites W2163862067 @default.
• W1548352846 cites W2163989133 @default.
• W1548352846 cites W2167560492 @default.
• W1548352846 cites W2167571044 @default.
• W1548352846 cites W2169292171 @default.
• W1548352846 cites W2596618906 @default.
• W1548352846 cites W4210453240 @default.
• W1548352846 cites W4233744435 @default.
• W1548352846 cites W4237885273 @default.
• W1548352846 cites W4254564610 @default.
• W1548352846 doi "https://doi.org/10.1002/14651858.cd009319.pub3" @default.
• W1548352846 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6478300" @default.
• W1548352846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28447767" @default.
• W1548352846 hasPublicationYear "2017" @default.
• W1548352846 type Work @default.
• W1548352846 sameAs 1548352846 @default.
• W1548352846 citedByCount "34" @default.
• W1548352846 countsByYear W15483528462012 @default.
• W1548352846 countsByYear W15483528462014 @default.
• W1548352846 countsByYear W15483528462015 @default.
• W1548352846 countsByYear W15483528462016 @default.
• W1548352846 countsByYear W15483528462017 @default.
• W1548352846 countsByYear W15483528462018 @default.
• W1548352846 countsByYear W15483528462019 @default.
• W1548352846 countsByYear W15483528462020 @default.
• W1548352846 countsByYear W15483528462021 @default.
• W1548352846 countsByYear W15483528462022 @default.
• W1548352846 countsByYear W15483528462023 @default.
• W1548352846 crossrefType "journal-article" @default.
• W1548352846 hasAuthorship W1548352846A5016185028 @default.
• W1548352846 hasAuthorship W1548352846A5019253871 @default.
• W1548352846 hasAuthorship W1548352846A5021433932 @default.
• W1548352846 hasAuthorship W1548352846A5025858111 @default.
• W1548352846 hasAuthorship W1548352846A5031431944 @default.
• W1548352846 hasAuthorship W1548352846A5063689978 @default.
• W1548352846 hasBestOaLocation W15483528462 @default.
• W1548352846 hasConcept C126322002 @default.
• W1548352846 hasConcept C126838900 @default.
• W1548352846 hasConcept C141071460 @default.
• W1548352846 hasConcept C168563851 @default.
• W1548352846 hasConcept C17744445 @default.
• W1548352846 hasConcept C199539241 @default.
• W1548352846 hasConcept C2775934546 @default.
• W1548352846 hasConcept C2776478404 @default.
• W1548352846 hasConcept C2779473830 @default.
• W1548352846 hasConcept C44249647 @default.
• W1548352846 hasConcept C535046627 @default.
• W1548352846 hasConcept C61434518 @default.
• W1548352846 hasConcept C71924100 @default.

• next