FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1548982016> ?p ?o ?g. }

• W1548982016 endingPage "499" @default.
• W1548982016 startingPage "492" @default.
• W1548982016 abstract "Carcinoid crises are rare life-threatening events involving cardiac instability when carcinoid tumours release vasoactive peptides. Such events can occur in the perioperative setting. Octreotide, a somatostatin analogue, is administered as a bolus dose of 100-500 μg iv or by infusion to treat carcinoid crises. Due to the apparent low risk-to-benefit profile, a much higher dose is sometimes used in urgent situations. The purpose of this study was to assess the evidence for administering doses or hourly infusions of octreotide that exceeded 1,500 μg iv to treat carcinoid crises. We also sought to identify which patients may require large doses and to describe the adverse effects of such doses.We systematically searched Medline, EMBASE, and Cochrane databases and hand-searched reference lists of relevant articles in 2006 and again in 2010 and 2011. All study designs were included in our search. Resolution of crisis symptoms was the primary outcome.Eighteen articles were included. No patient died during a carcinoid crisis. A retrospective chart review of 89 patients with carcinoid heart disease reported octreotide doses of 25-54,000 μg to treat carcinoid crises, although neither crisis symptoms nor outcomes were described.In the included case reports, carcinoid crises were managed effectively using octreotide 25-500 μg iv. Previous exposure to octreotide and carcinoid heart disease may warrant the need for higher doses. In addition to the low quality of the articles and the small sample size, inconsistent use of the term carcinoid crisis and paucity of reported outcomes were also limitations of this systematic review. These findings highlight the need for further investigation into dose-response relationships of octreotide for the treatment of carcinoid crisis." @default.
• W1548982016 created "2016-06-24" @default.
• W1548982016 creator A5001607408 @default.
• W1548982016 creator A5071292725 @default.
• W1548982016 date "2013-01-18" @default.
• W1548982016 modified "2023-10-10" @default.
• W1548982016 title "Mega-dose intravenous octreotide for the treatment of carcinoid crisis: a systematic review" @default.
• W1548982016 cites W1522835542 @default.
• W1548982016 cites W1938200258 @default.
• W1548982016 cites W1971863507 @default.
• W1548982016 cites W1973835782 @default.
• W1548982016 cites W1979423827 @default.
• W1548982016 cites W2005042277 @default.
• W1548982016 cites W2015681571 @default.
• W1548982016 cites W2021379779 @default.
• W1548982016 cites W2027730424 @default.
• W1548982016 cites W2030673962 @default.
• W1548982016 cites W2032776477 @default.
• W1548982016 cites W2034769448 @default.
• W1548982016 cites W2037964149 @default.
• W1548982016 cites W2052081199 @default.
• W1548982016 cites W2067086939 @default.
• W1548982016 cites W2070751590 @default.
• W1548982016 cites W2074327283 @default.
• W1548982016 cites W2083235937 @default.
• W1548982016 cites W2086287075 @default.
• W1548982016 cites W2091233971 @default.
• W1548982016 cites W2110922803 @default.
• W1548982016 cites W2117219637 @default.
• W1548982016 cites W2119451270 @default.
• W1548982016 cites W2133385424 @default.
• W1548982016 cites W2140741951 @default.
• W1548982016 cites W2143722442 @default.
• W1548982016 cites W2144185754 @default.
• W1548982016 cites W2149214723 @default.
• W1548982016 cites W2150511935 @default.
• W1548982016 cites W2152512207 @default.
• W1548982016 cites W2163783190 @default.
• W1548982016 cites W2407744734 @default.
• W1548982016 cites W4241902789 @default.
• W1548982016 cites W4294215472 @default.
• W1548982016 doi "https://doi.org/10.1007/s12630-012-9879-1" @default.
• W1548982016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23328959" @default.
• W1548982016 hasPublicationYear "2013" @default.
• W1548982016 type Work @default.
• W1548982016 sameAs 1548982016 @default.
• W1548982016 citedByCount "51" @default.
• W1548982016 countsByYear W15489820162013 @default.
• W1548982016 countsByYear W15489820162014 @default.
• W1548982016 countsByYear W15489820162015 @default.
• W1548982016 countsByYear W15489820162016 @default.
• W1548982016 countsByYear W15489820162017 @default.
• W1548982016 countsByYear W15489820162018 @default.
• W1548982016 countsByYear W15489820162019 @default.
• W1548982016 countsByYear W15489820162020 @default.
• W1548982016 countsByYear W15489820162021 @default.
• W1548982016 countsByYear W15489820162022 @default.
• W1548982016 crossrefType "journal-article" @default.
• W1548982016 hasAuthorship W1548982016A5001607408 @default.
• W1548982016 hasAuthorship W1548982016A5071292725 @default.
• W1548982016 hasBestOaLocation W15489820161 @default.
• W1548982016 hasConcept C126322002 @default.
• W1548982016 hasConcept C141071460 @default.
• W1548982016 hasConcept C177713679 @default.
• W1548982016 hasConcept C197934379 @default.
• W1548982016 hasConcept C2776297358 @default.
• W1548982016 hasConcept C2778506435 @default.
• W1548982016 hasConcept C2779066768 @default.
• W1548982016 hasConcept C2781025020 @default.
• W1548982016 hasConcept C2781151469 @default.
• W1548982016 hasConcept C2908862229 @default.
• W1548982016 hasConcept C2909397035 @default.
• W1548982016 hasConcept C31174226 @default.
• W1548982016 hasConcept C71924100 @default.
• W1548982016 hasConceptScore W1548982016C126322002 @default.
• W1548982016 hasConceptScore W1548982016C141071460 @default.
• W1548982016 hasConceptScore W1548982016C177713679 @default.
• W1548982016 hasConceptScore W1548982016C197934379 @default.
• W1548982016 hasConceptScore W1548982016C2776297358 @default.
• W1548982016 hasConceptScore W1548982016C2778506435 @default.
• W1548982016 hasConceptScore W1548982016C2779066768 @default.
• W1548982016 hasConceptScore W1548982016C2781025020 @default.
• W1548982016 hasConceptScore W1548982016C2781151469 @default.
• W1548982016 hasConceptScore W1548982016C2908862229 @default.
• W1548982016 hasConceptScore W1548982016C2909397035 @default.
• W1548982016 hasConceptScore W1548982016C31174226 @default.
• W1548982016 hasConceptScore W1548982016C71924100 @default.
• W1548982016 hasIssue "5" @default.
• W1548982016 hasLocation W15489820161 @default.
• W1548982016 hasLocation W15489820162 @default.
• W1548982016 hasOpenAccess W1548982016 @default.
• W1548982016 hasPrimaryLocation W15489820161 @default.
• W1548982016 hasRelatedWork W1875140348 @default.
• W1548982016 hasRelatedWork W2012038404 @default.
• W1548982016 hasRelatedWork W2059097754 @default.
• W1548982016 hasRelatedWork W2073518141 @default.
• W1548982016 hasRelatedWork W2152492492 @default.
• W1548982016 hasRelatedWork W2240476281 @default.

• next