Matches in SemOpenAlex for { <https://semopenalex.org/work/W1549069263> ?p ?o ?g. }
- W1549069263 endingPage "345" @default.
- W1549069263 startingPage "319" @default.
- W1549069263 abstract "Schizophrenia is a complex, debilitating neuropsychiatric disorder. Epidemiological, clinical, neuropsychological, and neurophysiological studies have provided substantial evidence that abnormalities in brain development and ongoing neuroplasticity play important roles in the pathogenesis of the disorder. Complementing these clinical studies, a range of cytoarchitectural, morphometric, ultrastructural, immunochemical, and gene expression methods have been applied in investigations of postmortem brain tissues to characterize the cellular and molecular profile of putative developmental and plastic abnormalities in schizophrenia. While findings have been diverse and many are in need of replication, investigations focusing on higher cortical and limbic brain regions are increasingly demonstrating abnormalities in the structural and molecular integrity of the synaptic complex as well as glutamate-related receptors and signal transduction pathways that play critical roles in brain development, synaptogenesis, and synaptic plasticity. Most exciting have been recent associations of schizophrenia with specific genes, such as neuregulin-1, dysbindin-1, and AKT-1, which are vital to synaptic development, neurotransmission, and plasticity." @default.
- W1549069263 created "2016-06-24" @default.
- W1549069263 creator A5060876408 @default.
- W1549069263 creator A5076399911 @default.
- W1549069263 creator A5088881304 @default.
- W1549069263 date "2005-01-01" @default.
- W1549069263 modified "2023-09-25" @default.
- W1549069263 title "Neurodevelopment, neuroplasticity, and new genes for schizophrenia" @default.
- W1549069263 cites W132008894 @default.
- W1549069263 cites W1511174464 @default.
- W1549069263 cites W1514573559 @default.
- W1549069263 cites W1535641516 @default.
- W1549069263 cites W15714334 @default.
- W1549069263 cites W1626173137 @default.
- W1549069263 cites W164290047 @default.
- W1549069263 cites W1665419471 @default.
- W1549069263 cites W1897589155 @default.
- W1549069263 cites W1907092125 @default.
- W1549069263 cites W1963956528 @default.
- W1549069263 cites W1964007647 @default.
- W1549069263 cites W1966407955 @default.
- W1549069263 cites W1967179993 @default.
- W1549069263 cites W1967466600 @default.
- W1549069263 cites W1967606063 @default.
- W1549069263 cites W1968983678 @default.
- W1549069263 cites W1969141861 @default.
- W1549069263 cites W1971032955 @default.
- W1549069263 cites W1971696611 @default.
- W1549069263 cites W1971916575 @default.
- W1549069263 cites W1972343960 @default.
- W1549069263 cites W1974262619 @default.
- W1549069263 cites W1974868817 @default.
- W1549069263 cites W1974992252 @default.
- W1549069263 cites W1975180862 @default.
- W1549069263 cites W1978212121 @default.
- W1549069263 cites W1978413536 @default.
- W1549069263 cites W1979496428 @default.
- W1549069263 cites W1981437105 @default.
- W1549069263 cites W1981719311 @default.
- W1549069263 cites W1982142654 @default.
- W1549069263 cites W1985037863 @default.
- W1549069263 cites W1985836432 @default.
- W1549069263 cites W1986331925 @default.
- W1549069263 cites W1987870555 @default.
- W1549069263 cites W1988486070 @default.
- W1549069263 cites W1989133472 @default.
- W1549069263 cites W1989700831 @default.
- W1549069263 cites W1990264946 @default.
- W1549069263 cites W1990883081 @default.
- W1549069263 cites W1991503782 @default.
- W1549069263 cites W1992073044 @default.
- W1549069263 cites W1992196139 @default.
- W1549069263 cites W1992507868 @default.
- W1549069263 cites W1993206740 @default.
- W1549069263 cites W1995540460 @default.
- W1549069263 cites W1996317885 @default.
- W1549069263 cites W1996717052 @default.
- W1549069263 cites W1997259111 @default.
- W1549069263 cites W2001486260 @default.
- W1549069263 cites W2002196550 @default.
- W1549069263 cites W2002305171 @default.
- W1549069263 cites W2002739553 @default.
- W1549069263 cites W2003960093 @default.
- W1549069263 cites W2004191360 @default.
- W1549069263 cites W2004715908 @default.
- W1549069263 cites W2006473500 @default.
- W1549069263 cites W2008291612 @default.
- W1549069263 cites W2010560152 @default.
- W1549069263 cites W2011692649 @default.
- W1549069263 cites W2012785062 @default.
- W1549069263 cites W2013025435 @default.
- W1549069263 cites W2015299692 @default.
- W1549069263 cites W2016662633 @default.
- W1549069263 cites W2016946796 @default.
- W1549069263 cites W2016996356 @default.
- W1549069263 cites W2017904964 @default.
- W1549069263 cites W2018912242 @default.
- W1549069263 cites W2018947767 @default.
- W1549069263 cites W2020237866 @default.
- W1549069263 cites W2021341799 @default.
- W1549069263 cites W2021366646 @default.
- W1549069263 cites W2022674223 @default.
- W1549069263 cites W2022704159 @default.
- W1549069263 cites W2023857352 @default.
- W1549069263 cites W2024215324 @default.
- W1549069263 cites W2024413432 @default.
- W1549069263 cites W2025904648 @default.
- W1549069263 cites W2026522842 @default.
- W1549069263 cites W2026696795 @default.
- W1549069263 cites W2026780520 @default.
- W1549069263 cites W2027669569 @default.
- W1549069263 cites W2027766570 @default.
- W1549069263 cites W2028352746 @default.
- W1549069263 cites W2028841212 @default.
- W1549069263 cites W2029084216 @default.
- W1549069263 cites W2030539523 @default.
- W1549069263 cites W2032208151 @default.
- W1549069263 cites W2032395354 @default.