Matches in SemOpenAlex for { <https://semopenalex.org/work/W1549197942> ?p ?o ?g. }
- W1549197942 abstract "Publisher Summary This chapter discusses onchocerciasis and lymphatic filariasis. Microfilariae of Onchocerca volvulus in superficial connective tissues, rather than in blood, are taken up by biting arthropod vectors, namely, the species of Simulium blackflies. There, they complete their development into third-stage infective juveniles. Infected vectors release 3L forms on biting new hosts, thereby completing the transmission cycle as 3L migrate and eventually mature to adults over a period of 6–12 months. In contrast, microfilariae of Wuchereria and Brugia circulate in peripheral blood, thereby completing their development to infective forms in a wide range of mosquito vectors. The 3L of these species migrate to lymphatic vessels maturing over a period of months. Eventually, they liberate microfilariae that make their way with the course of lymph flow into the peripheral blood. Live microfilariae of O. volvulus in enormous quantities may coexist with healthy human tissues, whereas severely affected onchocerciasis patients, disfigured and debilitated as a consequence of their infection, may have few or no live microfilariae detectable in their tissues." @default.
- W1549197942 created "2016-06-24" @default.
- W1549197942 creator A5022723144 @default.
- W1549197942 creator A5030507229 @default.
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- W1549197942 date "1994-01-01" @default.
- W1549197942 modified "2023-09-26" @default.
- W1549197942 title "Onchocerciasis and Lymphatic Filariasis" @default.
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