Matches in SemOpenAlex for { <https://semopenalex.org/work/W1549519005> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W1549519005 endingPage "3558" @default.
- W1549519005 startingPage "3558" @default.
- W1549519005 abstract "Malignant melanoma is an androgen-dependent tumor.1 Androgen blockade enhances response to the melanoma vaccine.2 In their study, Zhang et al reported that a history of teenage acne in women may be a novel risk factor for melanoma independent of other risk factors.3 Acne in women is related to androgens and can be treated with finasteride.4 Both finasteride and dutasteride prevent the conversion of testosterone to its tissue-active form, dihydrotestosterone, by inhibiting the enzyme 5-alpha reductase.5, 6 Dutasteride inhibits both isoforms of the enzyme, whereas finasteride inhibits only one. A personal history of prostate cancer increases the risk of melanoma.7 An analysis of Surveillance, Epidemiology, and End Results multiple primary standardized incidence ratios indicates that in white men aged ≥60 years with a benign or malignant prostate tumor, the observed-to-expected risk of subsequent melanoma was 1.20 in 1984 through 1989, 1.22 (P <.05) in 1990 through 1994, 1.12 (P <.05) in 1995 through 1999, 1.06 in 2000 through 2004, 1.02 in 2005 through 2009, and 1.02 in 2010 and beyond. The US Food and Drug Administration approved finasteride for sale in the United States in 1992 and dutasteride in 2001. Finasteride and dutasteride are widely prescribed for the treatment of benign prostatic hyperplasia. The use of these drugs may be associated with the decline in the risk of melanoma following prostate cancer that has been observed since 1984. No specific funding was disclosed. The authors made no disclosures. Steven Lehrer, MD Department of Radiation Oncology Icahn School of Medicine at Mount Sinai New York, New York" @default.
- W1549519005 created "2016-06-24" @default.
- W1549519005 creator A5075008841 @default.
- W1549519005 date "2015-06-08" @default.
- W1549519005 modified "2023-09-27" @default.
- W1549519005 title "Finasteride and dutasteride may reduce melanoma risk" @default.
- W1549519005 cites W107210901 @default.
- W1549519005 cites W1519995350 @default.
- W1549519005 cites W1998557711 @default.
- W1549519005 cites W2004042654 @default.
- W1549519005 cites W2045360813 @default.
- W1549519005 cites W2051592657 @default.
- W1549519005 cites W2082978771 @default.
- W1549519005 doi "https://doi.org/10.1002/cncr.29520" @default.
- W1549519005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26058811" @default.
- W1549519005 hasPublicationYear "2015" @default.
- W1549519005 type Work @default.
- W1549519005 sameAs 1549519005 @default.
- W1549519005 citedByCount "0" @default.
- W1549519005 crossrefType "journal-article" @default.
- W1549519005 hasAuthorship W1549519005A5075008841 @default.
- W1549519005 hasBestOaLocation W15495190051 @default.
- W1549519005 hasConcept C121608353 @default.
- W1549519005 hasConcept C126322002 @default.
- W1549519005 hasConcept C126894567 @default.
- W1549519005 hasConcept C143998085 @default.
- W1549519005 hasConcept C2775874879 @default.
- W1549519005 hasConcept C2776235491 @default.
- W1549519005 hasConcept C2777562237 @default.
- W1549519005 hasConcept C2777911890 @default.
- W1549519005 hasConcept C2778878792 @default.
- W1549519005 hasConcept C2779279991 @default.
- W1549519005 hasConcept C2779881493 @default.
- W1549519005 hasConcept C2780192828 @default.
- W1549519005 hasConcept C2780542891 @default.
- W1549519005 hasConcept C2910366748 @default.
- W1549519005 hasConcept C29456083 @default.
- W1549519005 hasConcept C71315377 @default.
- W1549519005 hasConcept C71924100 @default.
- W1549519005 hasConceptScore W1549519005C121608353 @default.
- W1549519005 hasConceptScore W1549519005C126322002 @default.
- W1549519005 hasConceptScore W1549519005C126894567 @default.
- W1549519005 hasConceptScore W1549519005C143998085 @default.
- W1549519005 hasConceptScore W1549519005C2775874879 @default.
- W1549519005 hasConceptScore W1549519005C2776235491 @default.
- W1549519005 hasConceptScore W1549519005C2777562237 @default.
- W1549519005 hasConceptScore W1549519005C2777911890 @default.
- W1549519005 hasConceptScore W1549519005C2778878792 @default.
- W1549519005 hasConceptScore W1549519005C2779279991 @default.
- W1549519005 hasConceptScore W1549519005C2779881493 @default.
- W1549519005 hasConceptScore W1549519005C2780192828 @default.
- W1549519005 hasConceptScore W1549519005C2780542891 @default.
- W1549519005 hasConceptScore W1549519005C2910366748 @default.
- W1549519005 hasConceptScore W1549519005C29456083 @default.
- W1549519005 hasConceptScore W1549519005C71315377 @default.
- W1549519005 hasConceptScore W1549519005C71924100 @default.
- W1549519005 hasIssue "19" @default.
- W1549519005 hasLocation W15495190051 @default.
- W1549519005 hasLocation W15495190052 @default.
- W1549519005 hasOpenAccess W1549519005 @default.
- W1549519005 hasPrimaryLocation W15495190051 @default.
- W1549519005 hasRelatedWork W1964928662 @default.
- W1549519005 hasRelatedWork W1986472546 @default.
- W1549519005 hasRelatedWork W2039849536 @default.
- W1549519005 hasRelatedWork W2104155137 @default.
- W1549519005 hasRelatedWork W2130335721 @default.
- W1549519005 hasRelatedWork W2151547940 @default.
- W1549519005 hasRelatedWork W2223219573 @default.
- W1549519005 hasRelatedWork W2768915954 @default.
- W1549519005 hasRelatedWork W2790785354 @default.
- W1549519005 hasRelatedWork W2474513771 @default.
- W1549519005 hasVolume "121" @default.
- W1549519005 isParatext "false" @default.
- W1549519005 isRetracted "false" @default.
- W1549519005 magId "1549519005" @default.
- W1549519005 workType "article" @default.