Matches in SemOpenAlex for { <https://semopenalex.org/work/W1549524497> ?p ?o ?g. }
- W1549524497 endingPage "481" @default.
- W1549524497 startingPage "475" @default.
- W1549524497 abstract "Gene retrocopies are generated by reverse transcription and genomic integration of mRNA. As such, retrocopies present an important exception to the central dogma of molecular biology, and have substantially impacted the functional landscape of the metazoan genome. While an estimated 8,000–17,000 retrocopies exist in the human genome reference sequence, the extent of variation between individuals in terms of retrocopy content has remained largely unexplored. Three recent studies by Abyzov et al., Ewing et al. and Schrider et al. have exploited 1,000 Genomes Project Consortium data, as well as other sources of whole‐genome sequencing data, to uncover novel gene retrocopies. Here, we compare the methods and results of these three studies, highlight the impact of retrocopies in human diversity and genome evolution, and speculate on the potential for somatic gene retrocopies to impact cancer etiology and genetic diversity among individual neurons in the mammalian brain." @default.
- W1549524497 created "2016-06-24" @default.
- W1549524497 creator A5007661384 @default.
- W1549524497 creator A5040882194 @default.
- W1549524497 creator A5052769777 @default.
- W1549524497 date "2014-02-25" @default.
- W1549524497 modified "2023-10-16" @default.
- W1549524497 title "Diversity through duplication: Whole‐genome sequencing reveals novel gene retrocopies in the human population" @default.
- W1549524497 cites W1509378838 @default.
- W1549524497 cites W1536915394 @default.
- W1549524497 cites W1944771638 @default.
- W1549524497 cites W1965141089 @default.
- W1549524497 cites W1971074826 @default.
- W1549524497 cites W1985515979 @default.
- W1549524497 cites W1986319478 @default.
- W1549524497 cites W1986929596 @default.
- W1549524497 cites W1988495745 @default.
- W1549524497 cites W1990379031 @default.
- W1549524497 cites W1991333931 @default.
- W1549524497 cites W2000945483 @default.
- W1549524497 cites W2004272492 @default.
- W1549524497 cites W2007569961 @default.
- W1549524497 cites W2007589425 @default.
- W1549524497 cites W2012300428 @default.
- W1549524497 cites W2015734897 @default.
- W1549524497 cites W2018177575 @default.
- W1549524497 cites W2018187946 @default.
- W1549524497 cites W2028190503 @default.
- W1549524497 cites W2032679533 @default.
- W1549524497 cites W2037794677 @default.
- W1549524497 cites W2040058302 @default.
- W1549524497 cites W2042661483 @default.
- W1549524497 cites W2045807857 @default.
- W1549524497 cites W2055821541 @default.
- W1549524497 cites W2057422817 @default.
- W1549524497 cites W2057844822 @default.
- W1549524497 cites W2058507386 @default.
- W1549524497 cites W2075224242 @default.
- W1549524497 cites W2077560413 @default.
- W1549524497 cites W2083224210 @default.
- W1549524497 cites W2086739233 @default.
- W1549524497 cites W2087056550 @default.
- W1549524497 cites W2089023364 @default.
- W1549524497 cites W2089471275 @default.
- W1549524497 cites W2093606206 @default.
- W1549524497 cites W2094454538 @default.
- W1549524497 cites W2095021929 @default.
- W1549524497 cites W2101763003 @default.
- W1549524497 cites W2102773855 @default.
- W1549524497 cites W2103973742 @default.
- W1549524497 cites W2113368041 @default.
- W1549524497 cites W2113973815 @default.
- W1549524497 cites W2114924552 @default.
- W1549524497 cites W2119390857 @default.
- W1549524497 cites W2119742125 @default.
- W1549524497 cites W2124056584 @default.
- W1549524497 cites W2129398737 @default.
- W1549524497 cites W2134143935 @default.
- W1549524497 cites W2137036621 @default.
- W1549524497 cites W2144392410 @default.
- W1549524497 cites W2145932909 @default.
- W1549524497 cites W2146892790 @default.
- W1549524497 cites W2147521158 @default.
- W1549524497 cites W2147575903 @default.
- W1549524497 cites W2150113817 @default.
- W1549524497 cites W2151750549 @default.
- W1549524497 cites W2152036273 @default.
- W1549524497 cites W2158485828 @default.
- W1549524497 cites W2161017601 @default.
- W1549524497 cites W2168263755 @default.
- W1549524497 cites W2168909179 @default.
- W1549524497 cites W2169674658 @default.
- W1549524497 cites W2171777347 @default.
- W1549524497 cites W2180747979 @default.
- W1549524497 doi "https://doi.org/10.1002/bies.201300181" @default.
- W1549524497 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4314676" @default.
- W1549524497 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24615986" @default.
- W1549524497 hasPublicationYear "2014" @default.
- W1549524497 type Work @default.
- W1549524497 sameAs 1549524497 @default.
- W1549524497 citedByCount "35" @default.
- W1549524497 countsByYear W15495244972014 @default.
- W1549524497 countsByYear W15495244972015 @default.
- W1549524497 countsByYear W15495244972016 @default.
- W1549524497 countsByYear W15495244972017 @default.
- W1549524497 countsByYear W15495244972019 @default.
- W1549524497 countsByYear W15495244972020 @default.
- W1549524497 countsByYear W15495244972021 @default.
- W1549524497 countsByYear W15495244972022 @default.
- W1549524497 countsByYear W15495244972023 @default.
- W1549524497 crossrefType "journal-article" @default.
- W1549524497 hasAuthorship W1549524497A5007661384 @default.
- W1549524497 hasAuthorship W1549524497A5040882194 @default.
- W1549524497 hasAuthorship W1549524497A5052769777 @default.
- W1549524497 hasBestOaLocation W15495244971 @default.
- W1549524497 hasConcept C104317684 @default.
- W1549524497 hasConcept C141231307 @default.
- W1549524497 hasConcept C144024400 @default.