FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1549559739> ?p ?o ?g. }

• W1549559739 endingPage "27268" @default.
• W1549559739 startingPage "27258" @default.
• W1549559739 abstract "Both positive and negative regulatory elements responsive to the product of the adenovirus type 12 E1A gene are located in the promoter region of the gene for mouse H-2Kbm1 major histocompatibility complex (MHC) class I antigen (1). We have analyzed the negative regulatory element that is affected by E1A and identified a target CAA repeated motif, CAA(A)CAAA, within -1725 to -1705 and -1591 to -1568 in a 316-bp sequence located in the far upstream region of H-2Kb promoter (-1837 to -1522; +1 refers to the cap site). The extent of cell surface expression of the MHC class 1 antigen was significantly decreased in the case of transfectants obtained by introducing an expression plasmid that included MHC class 1 cDNA with the CAA repeated element, as compared with that of a plasmid with mutated CAA repeats. We have also characterized the nuclear proteins that bind to this motif. The analysis of the effects of mutations during competition assays of in vivo and gel retardation competition assays demonstrated that the CAA repeated element is essential not only for E1A-dependent repression of transcription but also for the cell surface expression of the product of the mouse H-2Kb class I gene, presumably through nuclear proteins that specifically bind to it." @default.
• W1549559739 created "2016-06-24" @default.
• W1549559739 creator A5015282910 @default.
• W1549559739 creator A5017856719 @default.
• W1549559739 creator A5023412827 @default.
• W1549559739 creator A5025164221 @default.
• W1549559739 creator A5031503785 @default.
• W1549559739 creator A5049396535 @default.
• W1549559739 creator A5060373206 @default.
• W1549559739 creator A5066043834 @default.
• W1549559739 creator A5066117139 @default.
• W1549559739 creator A5071238165 @default.
• W1549559739 date "1993-12-01" @default.
• W1549559739 modified "2023-09-30" @default.
• W1549559739 title "Negative regulation of the gene for H-2Kb class I antigen by adenovirus 12-E1A is mediated by a CAA repeated element." @default.
• W1549559739 cites W1518790306 @default.
• W1549559739 cites W1546711220 @default.
• W1549559739 cites W1558516755 @default.
• W1549559739 cites W1560102264 @default.
• W1549559739 cites W1593099238 @default.
• W1549559739 cites W1606044738 @default.
• W1549559739 cites W1633720360 @default.
• W1549559739 cites W1821151738 @default.
• W1549559739 cites W1823869309 @default.
• W1549559739 cites W1962106317 @default.
• W1549559739 cites W1971436037 @default.
• W1549559739 cites W1980826960 @default.
• W1549559739 cites W1987358269 @default.
• W1549559739 cites W1988096490 @default.
• W1549559739 cites W1988844504 @default.
• W1549559739 cites W1993077558 @default.
• W1549559739 cites W1993243592 @default.
• W1549559739 cites W2027411626 @default.
• W1549559739 cites W2027569621 @default.
• W1549559739 cites W2040003193 @default.
• W1549559739 cites W2040714157 @default.
• W1549559739 cites W2052918890 @default.
• W1549559739 cites W2057125903 @default.
• W1549559739 cites W2060333964 @default.
• W1549559739 cites W2061735264 @default.
• W1549559739 cites W2061840195 @default.
• W1549559739 cites W2062947011 @default.
• W1549559739 cites W2066050654 @default.
• W1549559739 cites W2067769780 @default.
• W1549559739 cites W2069589902 @default.
• W1549559739 cites W2070173382 @default.
• W1549559739 cites W2072707236 @default.
• W1549559739 cites W2074005277 @default.
• W1549559739 cites W2074469271 @default.
• W1549559739 cites W2077700955 @default.
• W1549559739 cites W2080148314 @default.
• W1549559739 cites W2080711930 @default.
• W1549559739 cites W2082802847 @default.
• W1549559739 cites W2087828828 @default.
• W1549559739 cites W2088094960 @default.
• W1549559739 cites W2120479947 @default.
• W1549559739 cites W2138270253 @default.
• W1549559739 cites W2138820324 @default.
• W1549559739 cites W2140577948 @default.
• W1549559739 cites W2151920048 @default.
• W1549559739 cites W2157701908 @default.
• W1549559739 cites W2166801871 @default.
• W1549559739 cites W2333470849 @default.
• W1549559739 cites W2400691934 @default.
• W1549559739 cites W56197667 @default.
• W1549559739 doi "https://doi.org/10.1016/s0021-9258(19)74244-6" @default.
• W1549559739 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8262966" @default.
• W1549559739 hasPublicationYear "1993" @default.
• W1549559739 type Work @default.
• W1549559739 sameAs 1549559739 @default.
• W1549559739 citedByCount "18" @default.
• W1549559739 crossrefType "journal-article" @default.
• W1549559739 hasAuthorship W1549559739A5015282910 @default.
• W1549559739 hasAuthorship W1549559739A5017856719 @default.
• W1549559739 hasAuthorship W1549559739A5023412827 @default.
• W1549559739 hasAuthorship W1549559739A5025164221 @default.
• W1549559739 hasAuthorship W1549559739A5031503785 @default.
• W1549559739 hasAuthorship W1549559739A5049396535 @default.
• W1549559739 hasAuthorship W1549559739A5060373206 @default.
• W1549559739 hasAuthorship W1549559739A5066043834 @default.
• W1549559739 hasAuthorship W1549559739A5066117139 @default.
• W1549559739 hasAuthorship W1549559739A5071238165 @default.
• W1549559739 hasBestOaLocation W15495597391 @default.
• W1549559739 hasConcept C104317684 @default.
• W1549559739 hasConcept C147483822 @default.
• W1549559739 hasConcept C153911025 @default.
• W1549559739 hasConcept C159047783 @default.
• W1549559739 hasConcept C203014093 @default.
• W1549559739 hasConcept C54355233 @default.
• W1549559739 hasConcept C86803240 @default.
• W1549559739 hasConcept C95444343 @default.
• W1549559739 hasConceptScore W1549559739C104317684 @default.
• W1549559739 hasConceptScore W1549559739C147483822 @default.
• W1549559739 hasConceptScore W1549559739C153911025 @default.
• W1549559739 hasConceptScore W1549559739C159047783 @default.
• W1549559739 hasConceptScore W1549559739C203014093 @default.
• W1549559739 hasConceptScore W1549559739C54355233 @default.
• W1549559739 hasConceptScore W1549559739C86803240 @default.

• next