FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1549652159> ?p ?o ?g. }

• W1549652159 abstract "The structures of the altered alpha-melanotropin (alpha MSH or alpha-N-acetyl-ACTH(1-13)NH2)-related molecules produced by cultured rat intermediate pituitary cells were investigated. Peptide analyses demonstrated that the alpha MSH-related molecules produced by acutely prepared intermediate pituitary cells were primarily des-, mono-, and diacetylated ACTH(1-13)NH2; in contrast, longer term cultures produced primarily des-, mono-, and diacetylated ACTH(1-14)OH. No significant amount of labeled ACTH(1-13)OH-related material was observed under any incubation conditions. Intermediate pituitary cells in culture stopped producing alpha-amidated alpha MSH-related molecules with a half-time of approximately 15 to 18 h; instead, ACTH(1-14)OH-related molecules were synthesized. In several pulse-chase experiments, performed under conditions where cultured intermediate pituitary cells were capable of synthesizing alpha MSH-related molecules terminating in -Val13-NH2, labeled molecules ending in -Val13-Gly14-OH were not found to give rise to major amounts of labeled molecules ending in -Val13-NH2. This failure to observe conversion of glycine-extended molecules into alpha-amidated products was not due to selective secretion from the cells, since the acetylation and amidation states of labeled molecules that were secreted under basal conditions reflected those of the molecules stored in the cells, and the basal rate of secretion was very low." @default.
• W1549652159 created "2016-06-24" @default.
• W1549652159 creator A5011997610 @default.
• W1549652159 creator A5015706491 @default.
• W1549652159 creator A5023241754 @default.
• W1549652159 date "1983-06-01" @default.
• W1549652159 modified "2023-09-30" @default.
• W1549652159 title "Adrenocorticotropin(1-14)OH-related molecules in primary cultures of rat intermediate pituitary cells. Identification and role in the biosynthesis of alpha-melanotropin." @default.
• W1549652159 cites W1552666003 @default.
• W1549652159 cites W1554188317 @default.
• W1549652159 cites W1558554377 @default.
• W1549652159 cites W1571444008 @default.
• W1549652159 cites W1580814042 @default.
• W1549652159 cites W1591608900 @default.
• W1549652159 cites W1594945712 @default.
• W1549652159 cites W1631661863 @default.
• W1549652159 cites W1966946242 @default.
• W1549652159 cites W1971250912 @default.
• W1549652159 cites W1979458705 @default.
• W1549652159 cites W1983119903 @default.
• W1549652159 cites W1985515299 @default.
• W1549652159 cites W1998858772 @default.
• W1549652159 cites W2027427161 @default.
• W1549652159 cites W2041096899 @default.
• W1549652159 cites W2042158789 @default.
• W1549652159 cites W2051570638 @default.
• W1549652159 cites W2053807193 @default.
• W1549652159 cites W2068850166 @default.
• W1549652159 cites W2075110943 @default.
• W1549652159 cites W2087328208 @default.
• W1549652159 cites W2088428876 @default.
• W1549652159 cites W2102253483 @default.
• W1549652159 cites W2107336573 @default.
• W1549652159 cites W2134497688 @default.
• W1549652159 cites W2152848856 @default.
• W1549652159 cites W32187398 @default.
• W1549652159 doi "https://doi.org/10.1016/s0021-9258(18)32177-x" @default.
• W1549652159 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6305934" @default.
• W1549652159 hasPublicationYear "1983" @default.
• W1549652159 type Work @default.
• W1549652159 sameAs 1549652159 @default.
• W1549652159 citedByCount "33" @default.
• W1549652159 countsByYear W15496521592015 @default.
• W1549652159 countsByYear W15496521592016 @default.
• W1549652159 crossrefType "journal-article" @default.
• W1549652159 hasAuthorship W1549652159A5011997610 @default.
• W1549652159 hasAuthorship W1549652159A5015706491 @default.
• W1549652159 hasAuthorship W1549652159A5023241754 @default.
• W1549652159 hasBestOaLocation W15496521591 @default.
• W1549652159 hasConcept C104317684 @default.
• W1549652159 hasConcept C119157956 @default.
• W1549652159 hasConcept C134018914 @default.
• W1549652159 hasConcept C159110408 @default.
• W1549652159 hasConcept C178790620 @default.
• W1549652159 hasConcept C185592680 @default.
• W1549652159 hasConcept C202751555 @default.
• W1549652159 hasConcept C2775944032 @default.
• W1549652159 hasConcept C2777658017 @default.
• W1549652159 hasConcept C2777756961 @default.
• W1549652159 hasConcept C2779281246 @default.
• W1549652159 hasConcept C32909587 @default.
• W1549652159 hasConcept C49039625 @default.
• W1549652159 hasConcept C49453240 @default.
• W1549652159 hasConcept C515207424 @default.
• W1549652159 hasConcept C553450214 @default.
• W1549652159 hasConcept C55493867 @default.
• W1549652159 hasConcept C64943373 @default.
• W1549652159 hasConcept C71240020 @default.
• W1549652159 hasConcept C71315377 @default.
• W1549652159 hasConcept C71924100 @default.
• W1549652159 hasConcept C86803240 @default.
• W1549652159 hasConceptScore W1549652159C104317684 @default.
• W1549652159 hasConceptScore W1549652159C119157956 @default.
• W1549652159 hasConceptScore W1549652159C134018914 @default.
• W1549652159 hasConceptScore W1549652159C159110408 @default.
• W1549652159 hasConceptScore W1549652159C178790620 @default.
• W1549652159 hasConceptScore W1549652159C185592680 @default.
• W1549652159 hasConceptScore W1549652159C202751555 @default.
• W1549652159 hasConceptScore W1549652159C2775944032 @default.
• W1549652159 hasConceptScore W1549652159C2777658017 @default.
• W1549652159 hasConceptScore W1549652159C2777756961 @default.
• W1549652159 hasConceptScore W1549652159C2779281246 @default.
• W1549652159 hasConceptScore W1549652159C32909587 @default.
• W1549652159 hasConceptScore W1549652159C49039625 @default.
• W1549652159 hasConceptScore W1549652159C49453240 @default.
• W1549652159 hasConceptScore W1549652159C515207424 @default.
• W1549652159 hasConceptScore W1549652159C553450214 @default.
• W1549652159 hasConceptScore W1549652159C55493867 @default.
• W1549652159 hasConceptScore W1549652159C64943373 @default.
• W1549652159 hasConceptScore W1549652159C71240020 @default.
• W1549652159 hasConceptScore W1549652159C71315377 @default.
• W1549652159 hasConceptScore W1549652159C71924100 @default.
• W1549652159 hasConceptScore W1549652159C86803240 @default.
• W1549652159 hasLocation W15496521591 @default.
• W1549652159 hasOpenAccess W1549652159 @default.
• W1549652159 hasPrimaryLocation W15496521591 @default.
• W1549652159 hasRelatedWork W1494178313 @default.
• W1549652159 hasRelatedWork W1515063683 @default.
• W1549652159 hasRelatedWork W1552666003 @default.
• W1549652159 hasRelatedWork W1554188317 @default.

• next