FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1549671962> ?p ?o ?g. }

• W1549671962 endingPage "57" @default.
• W1549671962 startingPage "47" @default.
• W1549671962 abstract "Abstract Although severe hematologic and immunologic disorders occur in several viral infections, insight into the mechanisms by which viruses may affect hemopoietic tissues is poor. The previous demonstration of distinct immunohemopoietic lesions in mice with acute lymphocytic choriomeningitis (LCM) virus infection has led us to investigate the function of hemopoietic precursor cells in the course of this experimental infection. During the first week of infection, there was profound suppression of pluripotential stem cell (CFU) and in vitro colony-forming cell (CFU) compartments, and of 59Fe uptake into hemopoietic tissues. During the same period, we found enhanced activity of colony-stimulating factor, lack of responsiveness to erythropoietin, and appreciable titers of interferon in blood and spleen. After day 10 post infection, there was a striking increase in CFU and 59Fe uptake confined to spleen and blood. Restoration of bone marrow, however, was markedly delayed. With reference to recent studies on interferon, and the findings in mice with persistent LCM virus infection, we suggest that interferon may be the comprehensive suppressor of the hemopoietic precursor cells in the first stage of acute LCM virus infection, and that these cells in the recovery period are directed preferentially into erythropoiesis." @default.
• W1549671962 created "2016-06-24" @default.
• W1549671962 creator A5080308368 @default.
• W1549671962 creator A5082498642 @default.
• W1549671962 date "1977-01-01" @default.
• W1549671962 modified "2023-09-28" @default.
• W1549671962 title "Changes in hemopoiesis during the course of acute LCM virus infection in mice" @default.
• W1549671962 cites W1520314100 @default.
• W1549671962 cites W1534910096 @default.
• W1549671962 cites W1551513691 @default.
• W1549671962 cites W1587248324 @default.
• W1549671962 cites W1912212592 @default.
• W1549671962 cites W1933179245 @default.
• W1549671962 cites W1967413209 @default.
• W1549671962 cites W1978958721 @default.
• W1549671962 cites W1987444612 @default.
• W1549671962 cites W1988301594 @default.
• W1549671962 cites W2017221157 @default.
• W1549671962 cites W2021216059 @default.
• W1549671962 cites W2023754689 @default.
• W1549671962 cites W2024459923 @default.
• W1549671962 cites W2028088769 @default.
• W1549671962 cites W2030950508 @default.
• W1549671962 cites W2046920530 @default.
• W1549671962 cites W2060256167 @default.
• W1549671962 cites W2060860525 @default.
• W1549671962 cites W2118913754 @default.
• W1549671962 cites W2119086402 @default.
• W1549671962 cites W2131713113 @default.
• W1549671962 cites W2179053277 @default.
• W1549671962 cites W2181566467 @default.
• W1549671962 cites W2255489420 @default.
• W1549671962 cites W2313156595 @default.
• W1549671962 cites W2407567905 @default.
• W1549671962 cites W2427527473 @default.
• W1549671962 cites W2466698548 @default.
• W1549671962 cites W2097198765 @default.
• W1549671962 doi "https://doi.org/10.1182/blood.v49.1.47.47" @default.
• W1549671962 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/299734" @default.
• W1549671962 hasPublicationYear "1977" @default.
• W1549671962 type Work @default.
• W1549671962 sameAs 1549671962 @default.
• W1549671962 citedByCount "37" @default.
• W1549671962 countsByYear W15496719622013 @default.
• W1549671962 crossrefType "journal-article" @default.
• W1549671962 hasAuthorship W1549671962A5080308368 @default.
• W1549671962 hasAuthorship W1549671962A5082498642 @default.
• W1549671962 hasBestOaLocation W15496719621 @default.
• W1549671962 hasConcept C109159458 @default.
• W1549671962 hasConcept C126322002 @default.
• W1549671962 hasConcept C134018914 @default.
• W1549671962 hasConcept C159047783 @default.
• W1549671962 hasConcept C167672396 @default.
• W1549671962 hasConcept C203014093 @default.
• W1549671962 hasConcept C2522874641 @default.
• W1549671962 hasConcept C2776178377 @default.
• W1549671962 hasConcept C2778248108 @default.
• W1549671962 hasConcept C2778534260 @default.
• W1549671962 hasConcept C2779682186 @default.
• W1549671962 hasConcept C2779703530 @default.
• W1549671962 hasConcept C2780007613 @default.
• W1549671962 hasConcept C2780190958 @default.
• W1549671962 hasConcept C2780931953 @default.
• W1549671962 hasConcept C28328180 @default.
• W1549671962 hasConcept C54355233 @default.
• W1549671962 hasConcept C71924100 @default.
• W1549671962 hasConcept C86803240 @default.
• W1549671962 hasConcept C8891405 @default.
• W1549671962 hasConcept C95862172 @default.
• W1549671962 hasConceptScore W1549671962C109159458 @default.
• W1549671962 hasConceptScore W1549671962C126322002 @default.
• W1549671962 hasConceptScore W1549671962C134018914 @default.
• W1549671962 hasConceptScore W1549671962C159047783 @default.
• W1549671962 hasConceptScore W1549671962C167672396 @default.
• W1549671962 hasConceptScore W1549671962C203014093 @default.
• W1549671962 hasConceptScore W1549671962C2522874641 @default.
• W1549671962 hasConceptScore W1549671962C2776178377 @default.
• W1549671962 hasConceptScore W1549671962C2778248108 @default.
• W1549671962 hasConceptScore W1549671962C2778534260 @default.
• W1549671962 hasConceptScore W1549671962C2779682186 @default.
• W1549671962 hasConceptScore W1549671962C2779703530 @default.
• W1549671962 hasConceptScore W1549671962C2780007613 @default.
• W1549671962 hasConceptScore W1549671962C2780190958 @default.
• W1549671962 hasConceptScore W1549671962C2780931953 @default.
• W1549671962 hasConceptScore W1549671962C28328180 @default.
• W1549671962 hasConceptScore W1549671962C54355233 @default.
• W1549671962 hasConceptScore W1549671962C71924100 @default.
• W1549671962 hasConceptScore W1549671962C86803240 @default.
• W1549671962 hasConceptScore W1549671962C8891405 @default.
• W1549671962 hasConceptScore W1549671962C95862172 @default.
• W1549671962 hasIssue "1" @default.
• W1549671962 hasLocation W15496719621 @default.
• W1549671962 hasOpenAccess W1549671962 @default.
• W1549671962 hasPrimaryLocation W15496719621 @default.
• W1549671962 hasRelatedWork W1898885886 @default.
• W1549671962 hasRelatedWork W2018903526 @default.
• W1549671962 hasRelatedWork W2069741494 @default.
• W1549671962 hasRelatedWork W2081602378 @default.

• next