FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1549858049> ?p ?o ?g. }

• W1549858049 endingPage "68" @default.
• W1549858049 startingPage "359" @default.
• W1549858049 abstract "Mouse peritoneal macrophages (M phi) expressed enhanced tumoricidal activity upon in vitro stimulation either with the lymphokine M phi-activating factor (MAF) or with fibroblast interferon (IFN-beta). In contrast, M phi suppressive activity on lymphoproliferation was not affected by MAF pretreatment, but was drastically reduced or abolished by IFN-beta. Catalase, the enzyme involved in the destruction of hydrogen peroxide (H2O2), did significantly decrease M phi suppressive capacity but had no effect on M phi tumoricidal activity. Analysis of the phagocytosis-dependent H2O2 production by IFN-beta-treated M phi demonstrated a strong impairment of the oxygen metabolite release, which strictly paralleled the decreased M phi suppressive capacity. On the other hand, MAF did not modify H2O2 release by M phi. Studies on M phi antibacterial activity against Salmonella typhimurium, a function thought to depend upon H2O2 production, showed that exposure of M phi to IFN-beta significantly impaired their bactericidal and bacteriostatic capacity, again in close correlation with the decrease in H2O2 production. Thus, IFN-beta appears as modulating both suppressive and antibacterial capacities of M phi through reduction of their oxygen metabolism, whereas regulation of M phi anti-tumour activity is possibly controlled by different mechanisms." @default.
• W1549858049 created "2016-06-24" @default.
• W1549858049 creator A5013827500 @default.
• W1549858049 creator A5020722865 @default.
• W1549858049 creator A5024751307 @default.
• W1549858049 creator A5033064699 @default.
• W1549858049 creator A5043928949 @default.
• W1549858049 creator A5052765262 @default.
• W1549858049 creator A5057246307 @default.
• W1549858049 creator A5085080438 @default.
• W1549858049 date "1983-11-01" @default.
• W1549858049 modified "2023-09-27" @default.
• W1549858049 title "Interferon decreases production of hydrogen peroxide by macrophages: correlation with reduction of suppressive capacity and of anti-microbial activity." @default.
• W1549858049 cites W1479892159 @default.
• W1549858049 cites W1484814670 @default.
• W1549858049 cites W1493657798 @default.
• W1549858049 cites W1494462831 @default.
• W1549858049 cites W1519560107 @default.
• W1549858049 cites W1553654116 @default.
• W1549858049 cites W1558244799 @default.
• W1549858049 cites W1559111606 @default.
• W1549858049 cites W1573436053 @default.
• W1549858049 cites W1602391759 @default.
• W1549858049 cites W1915988257 @default.
• W1549858049 cites W1964054090 @default.
• W1549858049 cites W1972022723 @default.
• W1549858049 cites W1977875423 @default.
• W1549858049 cites W1980065068 @default.
• W1549858049 cites W1984271271 @default.
• W1549858049 cites W1997297528 @default.
• W1549858049 cites W1998862239 @default.
• W1549858049 cites W2003797153 @default.
• W1549858049 cites W2008681739 @default.
• W1549858049 cites W2017772699 @default.
• W1549858049 cites W2034082610 @default.
• W1549858049 cites W2098621632 @default.
• W1549858049 cites W2099408094 @default.
• W1549858049 cites W2153748987 @default.
• W1549858049 cites W2171070360 @default.
• W1549858049 cites W2174934515 @default.
• W1549858049 cites W2238291057 @default.
• W1549858049 cites W2396792658 @default.
• W1549858049 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1454272" @default.
• W1549858049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6354920" @default.
• W1549858049 hasPublicationYear "1983" @default.
• W1549858049 type Work @default.
• W1549858049 sameAs 1549858049 @default.
• W1549858049 citedByCount "9" @default.
• W1549858049 crossrefType "journal-article" @default.
• W1549858049 hasAuthorship W1549858049A5013827500 @default.
• W1549858049 hasAuthorship W1549858049A5020722865 @default.
• W1549858049 hasAuthorship W1549858049A5024751307 @default.
• W1549858049 hasAuthorship W1549858049A5033064699 @default.
• W1549858049 hasAuthorship W1549858049A5043928949 @default.
• W1549858049 hasAuthorship W1549858049A5052765262 @default.
• W1549858049 hasAuthorship W1549858049A5057246307 @default.
• W1549858049 hasAuthorship W1549858049A5085080438 @default.
• W1549858049 hasConcept C134018914 @default.
• W1549858049 hasConcept C160448771 @default.
• W1549858049 hasConcept C181199279 @default.
• W1549858049 hasConcept C185592680 @default.
• W1549858049 hasConcept C202751555 @default.
• W1549858049 hasConcept C203014093 @default.
• W1549858049 hasConcept C24998067 @default.
• W1549858049 hasConcept C2776178377 @default.
• W1549858049 hasConcept C2778979269 @default.
• W1549858049 hasConcept C48349386 @default.
• W1549858049 hasConcept C49382859 @default.
• W1549858049 hasConcept C533411734 @default.
• W1549858049 hasConcept C55493867 @default.
• W1549858049 hasConcept C86803240 @default.
• W1549858049 hasConcept C89423630 @default.
• W1549858049 hasConceptScore W1549858049C134018914 @default.
• W1549858049 hasConceptScore W1549858049C160448771 @default.
• W1549858049 hasConceptScore W1549858049C181199279 @default.
• W1549858049 hasConceptScore W1549858049C185592680 @default.
• W1549858049 hasConceptScore W1549858049C202751555 @default.
• W1549858049 hasConceptScore W1549858049C203014093 @default.
• W1549858049 hasConceptScore W1549858049C24998067 @default.
• W1549858049 hasConceptScore W1549858049C2776178377 @default.
• W1549858049 hasConceptScore W1549858049C2778979269 @default.
• W1549858049 hasConceptScore W1549858049C48349386 @default.
• W1549858049 hasConceptScore W1549858049C49382859 @default.
• W1549858049 hasConceptScore W1549858049C533411734 @default.
• W1549858049 hasConceptScore W1549858049C55493867 @default.
• W1549858049 hasConceptScore W1549858049C86803240 @default.
• W1549858049 hasConceptScore W1549858049C89423630 @default.
• W1549858049 hasIssue "3" @default.
• W1549858049 hasLocation W15498580491 @default.
• W1549858049 hasOpenAccess W1549858049 @default.
• W1549858049 hasPrimaryLocation W15498580491 @default.
• W1549858049 hasRelatedWork W1549858049 @default.
• W1549858049 hasRelatedWork W1550050965 @default.
• W1549858049 hasRelatedWork W1602007799 @default.
• W1549858049 hasRelatedWork W1925180248 @default.
• W1549858049 hasRelatedWork W2062794342 @default.
• W1549858049 hasRelatedWork W2070595079 @default.
• W1549858049 hasRelatedWork W2084283920 @default.

• next