Matches in SemOpenAlex for { <https://semopenalex.org/work/W1549942616> ?p ?o ?g. }
- W1549942616 endingPage "2787" @default.
- W1549942616 startingPage "2780" @default.
- W1549942616 abstract "A cis-dominant mutation in the adjacent E1a gene disrupted the accumulation of adenovirus type 5 E1b mRNA during the early phase of infection. Steady-state levels of cytoplasmic and nuclear E1b RNAs in cells infected with dl312, a strain that lacks the E1a TATA box, cap site, and much of the coding sequence, were reduced 5- to 10-fold even when the E1a activator was provided in trans. The strain was defective for early E1b RNA synthesis but not for E1b RNA made late or during prolonged incubation in the presence of an inhibitor of DNA replication. The defect in E1b RNA synthesis could not be attributed to the E1a promoter sequences missing in dl312 DNA. If the E1a protein-coding region contains cis-acting regulatory sequences, they are not part of the previously mapped E1b transcriptional control region and may represent additional regulatory elements that ensure prompt and efficient E1b expression during the early phase of infection." @default.
- W1549942616 created "2016-06-24" @default.
- W1549942616 creator A5020790264 @default.
- W1549942616 creator A5074045654 @default.
- W1549942616 date "1990-06-01" @default.
- W1549942616 modified "2023-09-26" @default.
- W1549942616 title "cis-dominant defect in activation of adenovirus type 5 E1b early RNA synthesis" @default.
- W1549942616 cites W1481502027 @default.
- W1549942616 cites W149924685 @default.
- W1549942616 cites W1527590544 @default.
- W1549942616 cites W1558516755 @default.
- W1549942616 cites W1570580692 @default.
- W1549942616 cites W1601687245 @default.
- W1549942616 cites W1608386720 @default.
- W1549942616 cites W179083412 @default.
- W1549942616 cites W1820433267 @default.
- W1549942616 cites W1824660776 @default.
- W1549942616 cites W1830661192 @default.
- W1549942616 cites W18314034 @default.
- W1549942616 cites W1894512455 @default.
- W1549942616 cites W19273212 @default.
- W1549942616 cites W1931663260 @default.
- W1549942616 cites W1956017529 @default.
- W1549942616 cites W1965372133 @default.
- W1549942616 cites W1967404701 @default.
- W1549942616 cites W1982558048 @default.
- W1549942616 cites W1995391727 @default.
- W1549942616 cites W1998385486 @default.
- W1549942616 cites W2003171435 @default.
- W1549942616 cites W2007281794 @default.
- W1549942616 cites W2007754578 @default.
- W1549942616 cites W2010675102 @default.
- W1549942616 cites W2010941083 @default.
- W1549942616 cites W2011715107 @default.
- W1549942616 cites W2014593543 @default.
- W1549942616 cites W2023226986 @default.
- W1549942616 cites W2026460545 @default.
- W1549942616 cites W2027955922 @default.
- W1549942616 cites W2032258076 @default.
- W1549942616 cites W2044296969 @default.
- W1549942616 cites W2046881557 @default.
- W1549942616 cites W2047842580 @default.
- W1549942616 cites W2050905927 @default.
- W1549942616 cites W2062147146 @default.
- W1549942616 cites W2065492425 @default.
- W1549942616 cites W2066780628 @default.
- W1549942616 cites W2067198866 @default.
- W1549942616 cites W2073446235 @default.
- W1549942616 cites W2075307129 @default.
- W1549942616 cites W207696562 @default.
- W1549942616 cites W2084099638 @default.
- W1549942616 cites W2084186257 @default.
- W1549942616 cites W2086404403 @default.
- W1549942616 cites W2089219831 @default.
- W1549942616 cites W2090554769 @default.
- W1549942616 cites W2092216600 @default.
- W1549942616 cites W2094154951 @default.
- W1549942616 cites W2103608510 @default.
- W1549942616 cites W2116951270 @default.
- W1549942616 cites W2130109620 @default.
- W1549942616 cites W2134926960 @default.
- W1549942616 cites W2137759749 @default.
- W1549942616 cites W2141201854 @default.
- W1549942616 cites W2151920048 @default.
- W1549942616 cites W2158224164 @default.
- W1549942616 cites W2158290831 @default.
- W1549942616 cites W2162934736 @default.
- W1549942616 cites W2165409475 @default.
- W1549942616 cites W2166613267 @default.
- W1549942616 cites W2218142690 @default.
- W1549942616 cites W2263684771 @default.
- W1549942616 cites W2306852714 @default.
- W1549942616 cites W2400691934 @default.
- W1549942616 cites W4211033454 @default.
- W1549942616 cites W4238841884 @default.
- W1549942616 doi "https://doi.org/10.1128/jvi.64.6.2780-2787.1990" @default.
- W1549942616 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/249458" @default.
- W1549942616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2139894" @default.
- W1549942616 hasPublicationYear "1990" @default.
- W1549942616 type Work @default.
- W1549942616 sameAs 1549942616 @default.
- W1549942616 citedByCount "12" @default.
- W1549942616 crossrefType "journal-article" @default.
- W1549942616 hasAuthorship W1549942616A5020790264 @default.
- W1549942616 hasAuthorship W1549942616A5074045654 @default.
- W1549942616 hasBestOaLocation W15499426161 @default.
- W1549942616 hasConcept C101762097 @default.
- W1549942616 hasConcept C104317684 @default.
- W1549942616 hasConcept C111599444 @default.
- W1549942616 hasConcept C138885662 @default.
- W1549942616 hasConcept C150194340 @default.
- W1549942616 hasConcept C153911025 @default.
- W1549942616 hasConcept C179926584 @default.
- W1549942616 hasConcept C194993378 @default.
- W1549942616 hasConcept C21592294 @default.
- W1549942616 hasConcept C2776954459 @default.
- W1549942616 hasConcept C41895202 @default.
- W1549942616 hasConcept C54355233 @default.