Matches in SemOpenAlex for { <https://semopenalex.org/work/W1549958612> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W1549958612 endingPage "72" @default.
- W1549958612 startingPage "70" @default.
- W1549958612 abstract "The Ras-Raf-Erk signaling pathway is essential for proper vulva development in C.elegans and proper response to stimuli in human cells. The importance of the conservation of these pathways shows how vulva development and cancer cells function like each other. The effect of Ras-Raf-Erk signaling in vulva development was examined by targeting pac-1 with RNAi and then quantifying the number of vulva protrusions. The results from the experiment showed that the loss of pac-1 inhibits ERK signaling in vulva development by decreasing the amount of vulva protrusions. This determined that normally pac-1 increases ERK signaling in vulva development. The Ras-Raf-Erk pathway is activated in cancer and further understanding of the targets of this pathway will help us better understand how cancer develops." @default.
- W1549958612 created "2016-06-24" @default.
- W1549958612 creator A5066097031 @default.
- W1549958612 creator A5086589515 @default.
- W1549958612 date "2012-03-25" @default.
- W1549958612 modified "2023-09-25" @default.
- W1549958612 title "pac-1 enhances Ras-Raf-Erk Signaling in C.elegan Vulval Cell Fate Patterning" @default.
- W1549958612 doi "https://doi.org/10.47611/jsr.v1i1.72" @default.
- W1549958612 hasPublicationYear "2012" @default.
- W1549958612 type Work @default.
- W1549958612 sameAs 1549958612 @default.
- W1549958612 citedByCount "0" @default.
- W1549958612 crossrefType "journal-article" @default.
- W1549958612 hasAuthorship W1549958612A5066097031 @default.
- W1549958612 hasAuthorship W1549958612A5086589515 @default.
- W1549958612 hasBestOaLocation W15499586121 @default.
- W1549958612 hasConcept C142724271 @default.
- W1549958612 hasConcept C2776316342 @default.
- W1549958612 hasConcept C502942594 @default.
- W1549958612 hasConcept C54355233 @default.
- W1549958612 hasConcept C57074206 @default.
- W1549958612 hasConcept C62112901 @default.
- W1549958612 hasConcept C62478195 @default.
- W1549958612 hasConcept C71924100 @default.
- W1549958612 hasConcept C86803240 @default.
- W1549958612 hasConcept C95444343 @default.
- W1549958612 hasConceptScore W1549958612C142724271 @default.
- W1549958612 hasConceptScore W1549958612C2776316342 @default.
- W1549958612 hasConceptScore W1549958612C502942594 @default.
- W1549958612 hasConceptScore W1549958612C54355233 @default.
- W1549958612 hasConceptScore W1549958612C57074206 @default.
- W1549958612 hasConceptScore W1549958612C62112901 @default.
- W1549958612 hasConceptScore W1549958612C62478195 @default.
- W1549958612 hasConceptScore W1549958612C71924100 @default.
- W1549958612 hasConceptScore W1549958612C86803240 @default.
- W1549958612 hasConceptScore W1549958612C95444343 @default.
- W1549958612 hasIssue "1" @default.
- W1549958612 hasLocation W15499586121 @default.
- W1549958612 hasOpenAccess W1549958612 @default.
- W1549958612 hasPrimaryLocation W15499586121 @default.
- W1549958612 hasRelatedWork W1976944452 @default.
- W1549958612 hasRelatedWork W1995672416 @default.
- W1549958612 hasRelatedWork W2000768456 @default.
- W1549958612 hasRelatedWork W2008661898 @default.
- W1549958612 hasRelatedWork W2047836069 @default.
- W1549958612 hasRelatedWork W2074887577 @default.
- W1549958612 hasRelatedWork W2240928903 @default.
- W1549958612 hasRelatedWork W2379238886 @default.
- W1549958612 hasRelatedWork W2389621368 @default.
- W1549958612 hasRelatedWork W2402544792 @default.
- W1549958612 hasRelatedWork W2411134029 @default.
- W1549958612 hasRelatedWork W2729685937 @default.
- W1549958612 hasRelatedWork W2743132962 @default.
- W1549958612 hasRelatedWork W2883217407 @default.
- W1549958612 hasRelatedWork W3022556852 @default.
- W1549958612 hasRelatedWork W3042072586 @default.
- W1549958612 hasRelatedWork W3103036291 @default.
- W1549958612 hasRelatedWork W3152956769 @default.
- W1549958612 hasRelatedWork W3168460642 @default.
- W1549958612 hasRelatedWork W45459971 @default.
- W1549958612 hasVolume "1" @default.
- W1549958612 isParatext "false" @default.
- W1549958612 isRetracted "false" @default.
- W1549958612 magId "1549958612" @default.
- W1549958612 workType "article" @default.