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• W1549998442 abstract "11 ABSTRACT IN FINNISH – TIIVISTELMA 13IN FINNISH – TIIVISTELMA 13 INTRODUCTION 15 REVIEW OF THE LITERATURE 19 1. LUNG CANCER 19 1.1 Epidemiology 19 1.2 Histology 21 1.3 Genetics and epigenetics 22 1.3.1 Methods used in the detection of genetic alterations and gene expression 26 1.3.2 Gene Ontology (GO) 28 2. ASBESTOS 28 2.1 Characteristics 28 2.2 Use 29 2.3 Toxicity and carcinogenicity 32 2.4 Asbestos and tobacco smoke as co-carcinogens 35 3. ASBESTOS-RELATED LUNG CANCER 35 3.1 Lung cancer risk associated with asbestos exposure .... 36 3.2 Clinical features 37 3.3 Molecular alterations attributable to asbestos exposure in lung cancer 38 3.3.1 Genetic alterations 38 3.3.2 Signalling pathways 41 AIMS OF THE STUDY 43 MATERIALS AND METHODS 44 1. LUNG CANCER PATIENTS AND DNA SAMPLES (I, II and III) 44 2. CELL LINES (IV) 47 2.1 Asbestos exposure 47" @default.
• W1549998442 created "2016-06-24" @default.
• W1549998442 creator A5018763133 @default.
• W1549998442 date "2010-06-11" @default.
• W1549998442 modified "2023-09-23" @default.
• W1549998442 title "Molecular Alterations in Asbestos-Related Lung Cancer" @default.
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