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- W155004817 abstract "Theoretical details are given of various oligogenic models for segregation analysis that are available as a general segregation analysis (GENSEG) package, programmed in FORTRAN iv. The models allow for up to two autosomal loci and one X-linked locus, normally distributed or dichotomous phenotypes, variable age of onset, and various ascertainment functions (including one that allows the probability of becoming a proband to be dependent on the age of onset). Current programs are limited to the analysis of 2-generational data, using the joint likelihood of the sibship and parental phenotypes, unless it can be assumed that the pedigrees being analyzed are a random sample from the population; half-sibships and twins, however, are explicitly allowed." @default.
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- W155004817 date "1975-01-01" @default.
- W155004817 modified "2023-10-12" @default.
- W155004817 title "General models for segregation analysis." @default.
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