FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1550065189> ?p ?o ?g. }

• W1550065189 endingPage "433" @default.
• W1550065189 startingPage "420" @default.
• W1550065189 abstract "Summary Sepsis is a leading cause of death in the intensive care unit (ICU), with Candida spp. in the forefront among the important pathogens. As recent studies have shown, survival outcome is strongly influenced by adequate antifungal therapy at an early stage that is often delayed by the time lag associated with microbiological diagnosis. Risk factor‐based prediction models have a high negative predictive value, but positive prediction of candidaemia in the individual patient remains elusive. New antigen‐ or DNA‐based methods for early diagnosis still await clinical validation. Their routine use is hampered by methodological issues. Species distribution of invasive Candida isolates in the ICU appears to be influenced primarily by age, previous hospitalisation and colonising species. In the context of the importance of adequate first‐line treatment, recent guidelines favour the use of echinocandins in critically ill patients with symptoms evoking high suspicion of invasive candidiasis. This is supported by robust clinical trial data, a few interactions and low toxicity. Fluconazole is characterised by reduced activity against some important Candida species, elevated rates of persistent infection seen in comparative trials. Amphotericin B deoxycholate should be considered obsolete in ICU patients because of its high toxicity. Invasive aspergillosis (IA) is a rare devastating infection in the general ICU population, but some centres have reported elevated incidences and underdiagnosis as determined in autopsy‐controlled studies. Treatment with mould‐active agents such as voriconazole must be initiated early in patients with suspected IA." @default.
• W1550065189 created "2016-06-24" @default.
• W1550065189 creator A5046402665 @default.
• W1550065189 creator A5069585976 @default.
• W1550065189 date "2011-09-01" @default.
• W1550065189 modified "2023-10-16" @default.
• W1550065189 title "Current aspects of invasive candidiasis and aspergillosis in adult intensive care patients" @default.
• W1550065189 cites W1485519026 @default.
• W1550065189 cites W1653248413 @default.
• W1550065189 cites W1804118339 @default.
• W1550065189 cites W1969836778 @default.
• W1550065189 cites W1971099675 @default.
• W1550065189 cites W1974953831 @default.
• W1550065189 cites W1979106685 @default.
• W1550065189 cites W1979297402 @default.
• W1550065189 cites W1979497376 @default.
• W1550065189 cites W1986442140 @default.
• W1550065189 cites W1995287041 @default.
• W1550065189 cites W1996843747 @default.
• W1550065189 cites W2000280458 @default.
• W1550065189 cites W2003661565 @default.
• W1550065189 cites W2008234991 @default.
• W1550065189 cites W2012383276 @default.
• W1550065189 cites W2013666547 @default.
• W1550065189 cites W2019847904 @default.
• W1550065189 cites W2027013717 @default.
• W1550065189 cites W2033083353 @default.
• W1550065189 cites W2035562817 @default.
• W1550065189 cites W2037167636 @default.
• W1550065189 cites W2039267791 @default.
• W1550065189 cites W2041927838 @default.
• W1550065189 cites W2042741618 @default.
• W1550065189 cites W2043774024 @default.
• W1550065189 cites W2051757474 @default.
• W1550065189 cites W2055113900 @default.
• W1550065189 cites W2069036995 @default.
• W1550065189 cites W2069061694 @default.
• W1550065189 cites W2071756060 @default.
• W1550065189 cites W2076924803 @default.
• W1550065189 cites W2079215889 @default.
• W1550065189 cites W2083352990 @default.
• W1550065189 cites W2087712604 @default.
• W1550065189 cites W2091326259 @default.
• W1550065189 cites W2092667553 @default.
• W1550065189 cites W2096894129 @default.
• W1550065189 cites W2098013607 @default.
• W1550065189 cites W2098505026 @default.
• W1550065189 cites W2104218588 @default.
• W1550065189 cites W2107803653 @default.
• W1550065189 cites W2108396393 @default.
• W1550065189 cites W2111216722 @default.
• W1550065189 cites W2112046323 @default.
• W1550065189 cites W2118236446 @default.
• W1550065189 cites W2120523595 @default.
• W1550065189 cites W2121247465 @default.
• W1550065189 cites W2123134253 @default.
• W1550065189 cites W2126319933 @default.
• W1550065189 cites W2127508258 @default.
• W1550065189 cites W2135175273 @default.
• W1550065189 cites W2136357460 @default.
• W1550065189 cites W2137575148 @default.
• W1550065189 cites W2139043187 @default.
• W1550065189 cites W2140505203 @default.
• W1550065189 cites W2141563676 @default.
• W1550065189 cites W2143599299 @default.
• W1550065189 cites W2145047464 @default.
• W1550065189 cites W2146558016 @default.
• W1550065189 cites W2150428940 @default.
• W1550065189 cites W2154371486 @default.
• W1550065189 cites W2156696455 @default.
• W1550065189 cites W2157860990 @default.
• W1550065189 cites W2164001967 @default.
• W1550065189 cites W2164404625 @default.
• W1550065189 cites W2166356134 @default.
• W1550065189 cites W2166806680 @default.
• W1550065189 cites W2167509781 @default.
• W1550065189 cites W2169453316 @default.
• W1550065189 cites W2171155970 @default.
• W1550065189 cites W2172027735 @default.
• W1550065189 cites W2172274380 @default.
• W1550065189 cites W2275269550 @default.
• W1550065189 cites W2340388705 @default.
• W1550065189 cites W3017100980 @default.
• W1550065189 cites W4211040615 @default.
• W1550065189 cites W4253591609 @default.
• W1550065189 doi "https://doi.org/10.1111/j.1439-0507.2010.01885.x" @default.
• W1550065189 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20492530" @default.
• W1550065189 hasPublicationYear "2011" @default.
• W1550065189 type Work @default.
• W1550065189 sameAs 1550065189 @default.
• W1550065189 citedByCount "21" @default.
• W1550065189 countsByYear W15500651892012 @default.
• W1550065189 countsByYear W15500651892013 @default.
• W1550065189 countsByYear W15500651892014 @default.
• W1550065189 countsByYear W15500651892015 @default.
• W1550065189 countsByYear W15500651892016 @default.
• W1550065189 countsByYear W15500651892018 @default.
• W1550065189 countsByYear W15500651892019 @default.

• next