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- W1550121732 abstract "Obesity is associated with hypertension, dyslipidemia, and diabetes, all of which are cardiovascular risk factors. Although obesity clusters with these risk factors, it also has its own independent and additional effect on the risk of cardiovascular events including myocardial infarction and stroke. Obesity and metabolic syndrome are also associated with sleep apnea. Diagnosis and treatment of sleep apnea can result in successful control of previously refractory hypertension. “Fitness” and “fatness” are both very important modifiable risk factors for vascular disease. However, fitness improves (perhaps halves) but does not completely abolish the cardiovascular risk of fatness. The concept of “syndrome Z” has been advanced to describe the combination of the metabolic “syndrome X” with OSA. This is a particularly dangerous combination creating a “perfect storm” of hypertension, sympathetic activation, and obesity related cardiomyopathy superimposed on a background of increased atherosclerotic risk and a pro-coagulant state." @default.
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- W1550121732 date "2013-04-01" @default.
- W1550121732 modified "2023-09-26" @default.
- W1550121732 title "Obesity and Cardiovascular Disease" @default.
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- W1550121732 doi "https://doi.org/10.1002/9781118643570.ch17" @default.
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