FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1550129947> ?p ?o ?g. }

• W1550129947 endingPage "32" @default.
• W1550129947 startingPage "827" @default.
• W1550129947 abstract "There is evidence from cytogenetic and loss of heterozygosity studies for the involvement of a tumor suppressor gene on chromosome 22 in the formation of meningiomas. Recently, the NF2 gene, which causes neurofibromatosis type 2 and which is located in the affected region on chromosome 22, has been identified. A previous study on 8 of the 17 exons of the NF2 gene described mutations in 16% of meningiomas. We have analyzed the entire coding region of the NF2 gene in 70 sporadic meningiomas and identified 43 mutations in 41 patients. These resulted predominantly in immediate truncation, splicing abnormalities, or an altered reading frame of the predicted protein product. Although there was no evidence for distinct hotspots, all mutations occurred in the first 13 exons, the region of homology with the filopodial proteins moesin, ezrin, and radixin. The association of loss of heterozygosity on chromosome 22 with mutations in the NF2 gene was significant. These data suggest that NF2 represents the meningioma locus on chromosome 22. NF2 mutations occurred significantly more frequently in fibroblastic meningioma (70%) and transitional meningioma (83%) than in meningiothelial meningioma (25%), thus indicating a differential molecular pathogenesis of these meningioma variants." @default.
• W1550129947 created "2016-06-24" @default.
• W1550129947 creator A5005648435 @default.
• W1550129947 creator A5007043030 @default.
• W1550129947 creator A5011818435 @default.
• W1550129947 creator A5017575332 @default.
• W1550129947 creator A5021122229 @default.
• W1550129947 creator A5044329623 @default.
• W1550129947 creator A5055989777 @default.
• W1550129947 creator A5056489448 @default.
• W1550129947 creator A5062981284 @default.
• W1550129947 creator A5069752650 @default.
• W1550129947 date "1995-04-01" @default.
• W1550129947 modified "2023-10-03" @default.
• W1550129947 title "Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma." @default.
• W1550129947 cites W1573861051 @default.
• W1550129947 cites W1587406854 @default.
• W1550129947 cites W1661742470 @default.
• W1550129947 cites W1757036739 @default.
• W1550129947 cites W1971199253 @default.
• W1550129947 cites W1995263093 @default.
• W1550129947 cites W2001375335 @default.
• W1550129947 cites W2029976610 @default.
• W1550129947 cites W2070452292 @default.
• W1550129947 cites W2070491420 @default.
• W1550129947 cites W2071456395 @default.
• W1550129947 cites W2071639722 @default.
• W1550129947 cites W2155457011 @default.
• W1550129947 cites W2158510547 @default.
• W1550129947 cites W2161807488 @default.
• W1550129947 cites W2312541151 @default.
• W1550129947 cites W2411229614 @default.
• W1550129947 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1869258" @default.
• W1550129947 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7717450" @default.
• W1550129947 hasPublicationYear "1995" @default.
• W1550129947 type Work @default.
• W1550129947 sameAs 1550129947 @default.
• W1550129947 citedByCount "92" @default.
• W1550129947 countsByYear W15501299472012 @default.
• W1550129947 countsByYear W15501299472013 @default.
• W1550129947 countsByYear W15501299472014 @default.
• W1550129947 countsByYear W15501299472016 @default.
• W1550129947 countsByYear W15501299472017 @default.
• W1550129947 countsByYear W15501299472018 @default.
• W1550129947 countsByYear W15501299472019 @default.
• W1550129947 countsByYear W15501299472020 @default.
• W1550129947 countsByYear W15501299472021 @default.
• W1550129947 countsByYear W15501299472022 @default.
• W1550129947 countsByYear W15501299472023 @default.
• W1550129947 crossrefType "journal-article" @default.
• W1550129947 hasAuthorship W1550129947A5005648435 @default.
• W1550129947 hasAuthorship W1550129947A5007043030 @default.
• W1550129947 hasAuthorship W1550129947A5011818435 @default.
• W1550129947 hasAuthorship W1550129947A5017575332 @default.
• W1550129947 hasAuthorship W1550129947A5021122229 @default.
• W1550129947 hasAuthorship W1550129947A5044329623 @default.
• W1550129947 hasAuthorship W1550129947A5055989777 @default.
• W1550129947 hasAuthorship W1550129947A5056489448 @default.
• W1550129947 hasAuthorship W1550129947A5062981284 @default.
• W1550129947 hasAuthorship W1550129947A5069752650 @default.
• W1550129947 hasConcept C104317684 @default.
• W1550129947 hasConcept C142724271 @default.
• W1550129947 hasConcept C143589142 @default.
• W1550129947 hasConcept C180754005 @default.
• W1550129947 hasConcept C2778679214 @default.
• W1550129947 hasConcept C2778984943 @default.
• W1550129947 hasConcept C2779160599 @default.
• W1550129947 hasConcept C2994225774 @default.
• W1550129947 hasConcept C30481170 @default.
• W1550129947 hasConcept C36823959 @default.
• W1550129947 hasConcept C501734568 @default.
• W1550129947 hasConcept C54355233 @default.
• W1550129947 hasConcept C54815482 @default.
• W1550129947 hasConcept C71924100 @default.
• W1550129947 hasConcept C84597430 @default.
• W1550129947 hasConcept C86803240 @default.
• W1550129947 hasConceptScore W1550129947C104317684 @default.
• W1550129947 hasConceptScore W1550129947C142724271 @default.
• W1550129947 hasConceptScore W1550129947C143589142 @default.
• W1550129947 hasConceptScore W1550129947C180754005 @default.
• W1550129947 hasConceptScore W1550129947C2778679214 @default.
• W1550129947 hasConceptScore W1550129947C2778984943 @default.
• W1550129947 hasConceptScore W1550129947C2779160599 @default.
• W1550129947 hasConceptScore W1550129947C2994225774 @default.
• W1550129947 hasConceptScore W1550129947C30481170 @default.
• W1550129947 hasConceptScore W1550129947C36823959 @default.
• W1550129947 hasConceptScore W1550129947C501734568 @default.
• W1550129947 hasConceptScore W1550129947C54355233 @default.
• W1550129947 hasConceptScore W1550129947C54815482 @default.
• W1550129947 hasConceptScore W1550129947C71924100 @default.
• W1550129947 hasConceptScore W1550129947C84597430 @default.
• W1550129947 hasConceptScore W1550129947C86803240 @default.
• W1550129947 hasIssue "4" @default.
• W1550129947 hasLocation W15501299471 @default.
• W1550129947 hasOpenAccess W1550129947 @default.
• W1550129947 hasPrimaryLocation W15501299471 @default.
• W1550129947 hasRelatedWork W1550129947 @default.
• W1550129947 hasRelatedWork W1601342440 @default.

• next