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- W1550875302 abstract "textabstractAllergic asthma is a chronic inflammatory disorder of the airways in response to inhaled allergensand is characterized by airway inflammation, bronchial hyperresponsiveness and a variabledegree of airflow obstruction, leading to episodes of wheezing, coughing and breathlessness.In addition, structural changes (‘airway remodeling’) in the airway including subepithelialand airway wall fibrosis, goblet cell hyperplasia/metaplasia, smooth muscle thickening andincreased vascularity are observed. In susceptible individuals, repeated exposure to harmlessenvironmental allergens like house-dust mites (HDMs), molds, plant pollen and animal dandercan lead to sensitization and development of a chronic immune response consisting of aneffector cascade leading to immediate and late-phase reactions to allergens and subsequentcharacteristic clinical symptoms." @default.
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- W1550875302 date "2012-12-14" @default.
- W1550875302 modified "2023-09-27" @default.
- W1550875302 title "Induction of immunoglobulin A as a therapeutic intervention in allergic asthma" @default.
- W1550875302 hasPublicationYear "2012" @default.
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