FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1551005087> ?p ?o ?g. }

• W1551005087 endingPage "194" @default.
• W1551005087 startingPage "191" @default.
• W1551005087 abstract "The aim of our study was to evaluate the metabolic profile of brain tissue of two long-term survivors of childhood brain tumors.Two males who were 25 and 33 years old at the time of examination and had been irradiated for brain tumors at the age of 17 and 13 years respectively. The first subject had been operated on radically for medulloblastoma and received craniospinal axis irradiation composed of a whole brain radiotherapy with boost to the posterior fossa (total dose (TD) = 59.4 Gy in 33 fractions) and spinal canal irradiation (TD = 30 Gy in 20 fractions) according to the protocol at the time of treatment. The second subject had previously received whole brain irradiation (TD = 45 Gy in 19 fractions) because of inoperable central region tumor of unknown histology.Short echo-time (TE = 30 ms) point-resolved spectra were obtained using a 2 T magnet. Ratios of N-acetylaspartate (NAA), choline (Cho), myo-inositol (mI), lactate (Lac) and lipids (Lip) signal intensities were calculated using the creatine (Cr) signal as an internal reference. The spectra were acquired both from the tumor bed area and uninvolved brain tissue in the first subject, and from uninvolved brain areas of frontal and occipital lobes in the second subject.In both cases, MRS examination revealed ratios of NAA/Cr, Cho/Cr and mI/Cr within normal range in most spectra. Nevertheless, a slight elevation of Lac/Cr (2.47 and 1.05) and a more pronounced elevation of Lip/Cr proportions (45.77 and 3.97 respectively, in uninvolved sites) were detected in both patients.Metabolic parameters correlated with neuronal function (NAA/Cr) and cell membrane metabolites turnover (Cho/Cr) seem to recover to normal values in long-term survivors of brain tumors. Lac/Cr and Lip/Cr proportions could be considered parameters indicating permanent radiation-induced brain damage; however, this proposal requires further investigation." @default.
• W1551005087 created "2016-06-24" @default.
• W1551005087 creator A5005623067 @default.
• W1551005087 creator A5040459781 @default.
• W1551005087 creator A5053792570 @default.
• W1551005087 creator A5079421605 @default.
• W1551005087 creator A5081549240 @default.
• W1551005087 date "2009-08-31" @default.
• W1551005087 modified "2023-10-17" @default.
• W1551005087 title "Magnetic Resonance Spectroscopic Evaluation of Brain Tissue Metabolism After Irradiation for Pediatric Brain Tumors in Long-Term Survivors: A Report of Two Cases" @default.
• W1551005087 cites W1236920222 @default.
• W1551005087 cites W1970536878 @default.
• W1551005087 cites W1983539927 @default.
• W1551005087 cites W1994232202 @default.
• W1551005087 cites W2004824110 @default.
• W1551005087 cites W2010808589 @default.
• W1551005087 cites W2021318411 @default.
• W1551005087 cites W2036167723 @default.
• W1551005087 cites W2063659733 @default.
• W1551005087 cites W2094131569 @default.
• W1551005087 cites W2119618786 @default.
• W1551005087 cites W2126496077 @default.
• W1551005087 cites W2128704027 @default.
• W1551005087 cites W2139806709 @default.
• W1551005087 cites W2139880800 @default.
• W1551005087 cites W2141464097 @default.
• W1551005087 doi "https://doi.org/10.1007/978-3-211-98811-4_35" @default.
• W1551005087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19812947" @default.
• W1551005087 hasPublicationYear "2009" @default.
• W1551005087 type Work @default.
• W1551005087 sameAs 1551005087 @default.
• W1551005087 citedByCount "1" @default.
• W1551005087 countsByYear W15510050872021 @default.
• W1551005087 crossrefType "book-chapter" @default.
• W1551005087 hasAuthorship W1551005087A5005623067 @default.
• W1551005087 hasAuthorship W1551005087A5040459781 @default.
• W1551005087 hasAuthorship W1551005087A5053792570 @default.
• W1551005087 hasAuthorship W1551005087A5079421605 @default.
• W1551005087 hasAuthorship W1551005087A5081549240 @default.
• W1551005087 hasConcept C126322002 @default.
• W1551005087 hasConcept C126838900 @default.
• W1551005087 hasConcept C142724271 @default.
• W1551005087 hasConcept C143409427 @default.
• W1551005087 hasConcept C2779130545 @default.
• W1551005087 hasConcept C2779896295 @default.
• W1551005087 hasConcept C2780789225 @default.
• W1551005087 hasConcept C2781123555 @default.
• W1551005087 hasConcept C2989005 @default.
• W1551005087 hasConcept C509974204 @default.
• W1551005087 hasConcept C71924100 @default.
• W1551005087 hasConceptScore W1551005087C126322002 @default.
• W1551005087 hasConceptScore W1551005087C126838900 @default.
• W1551005087 hasConceptScore W1551005087C142724271 @default.
• W1551005087 hasConceptScore W1551005087C143409427 @default.
• W1551005087 hasConceptScore W1551005087C2779130545 @default.
• W1551005087 hasConceptScore W1551005087C2779896295 @default.
• W1551005087 hasConceptScore W1551005087C2780789225 @default.
• W1551005087 hasConceptScore W1551005087C2781123555 @default.
• W1551005087 hasConceptScore W1551005087C2989005 @default.
• W1551005087 hasConceptScore W1551005087C509974204 @default.
• W1551005087 hasConceptScore W1551005087C71924100 @default.
• W1551005087 hasLocation W15510050871 @default.
• W1551005087 hasLocation W15510050872 @default.
• W1551005087 hasOpenAccess W1551005087 @default.
• W1551005087 hasPrimaryLocation W15510050871 @default.
• W1551005087 hasRelatedWork W1968381353 @default.
• W1551005087 hasRelatedWork W1975249752 @default.
• W1551005087 hasRelatedWork W2083088629 @default.
• W1551005087 hasRelatedWork W2384063274 @default.
• W1551005087 hasRelatedWork W2409787923 @default.
• W1551005087 hasRelatedWork W2888634671 @default.
• W1551005087 hasRelatedWork W3143052064 @default.
• W1551005087 hasRelatedWork W3164277805 @default.
• W1551005087 hasRelatedWork W4281934300 @default.
• W1551005087 hasRelatedWork W655668084 @default.
• W1551005087 isParatext "false" @default.
• W1551005087 isRetracted "false" @default.
• W1551005087 magId "1551005087" @default.
• W1551005087 workType "book-chapter" @default.