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- W1551018045 abstract "Pulmonary vein (PV) isolation by elimination of spike potentials has been reported to cure drug refractory atrial fibrillation. Because of the heterogenous morphology of the PVs, sequential electroanatomic reconstruction of the PVs was performed in 39 patients (group A), who underwent subsequent PV isolation by interruption of all conductive myocardial fibers by distinct RF current applications using a lasso approach. In group B (157 patients), only biplane two-dimensional fluoroscopy was performed to guide the diagnostic and the ablation catheters. After reprocedures (in 7% of patients in group A and 22% of group B), which depicted a recurrence of a spike potential inside or at the ostium of >1 previously isolated PV in all restudied patients, stable sinus rhythm was documented in 69% of patients in group A and 60% of patients in group B. Reasons for the relapse of the previously eliminated spike potentials include a temporary ablation effect and a too distal interruption of the conducting myocardial fiber. Detailed knowledge of the individual three-dimensional morphology enhanced the clinical success rate of PV isolation but is time-consuming using CARTO (8.0 +/- 1.7 vs 5.0 +/- 1.6, P < 0.001). Further technical improvement to fuse the individual three-dimensional anatomy and the electrophysiological markers to a composed electroanatomic map may overcome this limitation in the future." @default.
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- W1551018045 date "2003-06-30" @default.
- W1551018045 modified "2023-10-15" @default.
- W1551018045 title "Ostial PV Isolation:. Is There a Role for Three-Dimensional Mapping?" @default.
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- W1551018045 doi "https://doi.org/10.1046/j.1460-9592.2003.t01-1-00242.x" @default.
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