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- W1551118511 abstract "The effects of the factors time, sodium fluoride concentration, ethanol concentration, temperature of storage and type of container on the ethanol losses from stored human blood have been investigated by means of a 25 factorial experiment. The important factors were found to be temperature, fluoride concentration and time of storage. A detailed study of the important factors enabled three distinct mechanisms of ethanol loss to be identified. These were a highly temperature-dependent ethanol oxidation reaction which was independent of the ethanol concentration over a wide range; destruction of ethanol by the action of micro-organisms in the absence of a preservative, which could be inhibited by 0.5% (w/v) sodium fluoride, and diffusion which was found to occur from 5.6% of the polypropylene containers used in Britain for the purposes of the Road Traffic Act 1972. On examine l'influence de divers facteurs: temps, concentration en fluorure de sodium, concentration en éthanol, température de stockage et type du récipient, sur les pertes en éthanol de sang humain stocké. Les plus importants sont la température, la concentration en fluorure et la durée du stockage. Une étude détaillée de ces facteurs a permis d'établir trois mécanismes distincts de perte d'éthanol: réaction d'oxydation de l'éthanol très dépendante de température; destruction de l'éthanol par action de micro-organismes, en l'absence de préservatif et diffusion dans des récipients de polypropylène. Der Einfluss der Faktoren Zeit, Natriumfluoridkonzentration, Äthanolkonzentration, Lagertemperatur und Gefässart auf die Äthanolverluste in aufbewahrtem menschlichem Blut wurde mit Hilfe eines 25-Faktoriellen-Experimentes untersucht. Als wichtige Faktoren wurden die Temperatur, Fluoridkonzentration und Lagerzeit ermittelt. Durch genaue Untersuchung der wichtigen Faktoren wurden drei verschiedene Mechanismen des Äthanolverlustes festgestellt. Diese waren eine stark temperaturabhängige Äthanoloxidationsreaktion, die in einem weiten Bereich von der Äthanolkonzentration unabhängig war Äthanolverlust durch die Wirkung von Mikroorganismen in Abwesenheit eines Schutzmittels, der durch 0.5% (G/V) Natriumfluorid verhindert werden konnte, und Diffusion, die bei 5.6% der verwendeten Polypropylengefässe auftrat." @default.
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- W1551118511 date "1973-09-01" @default.
- W1551118511 modified "2023-09-27" @default.
- W1551118511 title "The stability of ethanol in stored blood" @default.
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- W1551118511 doi "https://doi.org/10.1016/s0003-2670(01)82539-3" @default.
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