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• W1551894966 abstract "Background: Epidermodysplasia verruciformis (EV) is a rare genodermatosis associated to human papillomaviruses (HPV). lt has been detected in benign and premalignant lesions associated to EV. Objective: To investigate the presence of EV-associated HPV DNA in benign lesions and to elucidate the presence of distinct HPV genotypes. Material and methods: We investigated 8 skin biopsies in EV-patients, to determine HPV-DNA using a polymerase chain reaction. HPV genotypes were identified by direct sequencing. Results: EV-associated HPV DNA was detected in all skin biopsies (8 patients, 100%). Two distinct HPV genotypes were detected in the skin biopsies: HPV 5 and 8. Conclusions: This study provides evidence that EV-associated HPVs play a role in the pathogenesis of EV." @default.
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• W1551894966 date "2006-01-01" @default.
• W1551894966 modified "2023-09-23" @default.
• W1551894966 title "Epidermodisplasia verruciforme. Modelo de carcinogenesis viral" @default.
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