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- W1551982006 abstract "Purpose To study the long-term results (1–14 years) of trabeculectomies with 5-fluorouracil injections that were successful at 1 year. Design A retrospective noncomparative case series. Intervention/participants We identified 87 patients (87 eyes) who had trabeculectomies with 5-fluorouracil injections from 1984 to 1989 that were successful at 1 year and had a follow-up range of 1.0 to 14.7 years (mean, 8.1, standard deviation of 4.4 years). All patients had previously failed glaucoma surgery (66.7%), cataract surgery (47.1%), or other diagnoses making them at high risk for failure. Main outcome measures Successful control of intraocular pressure (IOP) was defined as IOP less than 21 mmHg or a reduction of 33% if preoperative pressure was less than 21 mmHg. Statistical analysis was performed using Kaplan-Meier life table analysis. Results If an eye is considered successful by IOP at 1 year, the probability of successful control is 61% at 5 years, 44% at 10 years, and 41% at 14 years. Conclusions Despite successful IOP control at 1 year, trabeculectomies with 5-fluorouracil injections show a continual loss of IOP control over time." @default.
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- W1551982006 date "2002-10-01" @default.
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- W1551982006 title "Long-term follow-up of initially successful trabeculectomy with 5-fluorouracil injections1 1The authors have no proprietary interest in any of the materials used in this study." @default.
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- W1551982006 doi "https://doi.org/10.1016/s0161-6420(02)01186-7" @default.
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