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- W1551993438 abstract "In addition to advancing our understanding of RCC, improved abdominal imaging technology has caused a migration of tumor stage and alteration of surgical strategies, with tumors commonly being diagnosed at an earlier stage. Despite these advances, the prognosis for patients with metastatic RCC is poor. Of the total number of patients with renal cancer, approximately a third either presents with or later develops metastatic disease. Unfortunately, for these patients, contemporary systemic therapies are generally ineffective—median survival is less than 1 year. Despite adjuvant systemic chemotherapy, hormonal or cytokine therapies, used alone or in combination, overall response rates rarely exceed 20% and durable, complete responses are rare. Targeted therapy in the management of metastatic renal cell cancer is newly introduced to urology practise. These drugs were used in very limited number of patients and only for clear cell histology. No recommendation to use these drugs for other than clear cell histology was seen in the literature. Nevertheless, there is a encouraging responses in trials with limited number of patients in the literature. Future advances are expected." @default.
- W1551993438 created "2016-06-24" @default.
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- W1551993438 date "2012-02-03" @default.
- W1551993438 modified "2023-10-18" @default.
- W1551993438 title "Contemporary Management in Metastatic Renal Cell Carcinoma" @default.
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- W1551993438 doi "https://doi.org/10.5772/28179" @default.
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