FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1552015334> ?p ?o ?g. }

• W1552015334 endingPage "3" @default.
• W1552015334 startingPage "3" @default.
• W1552015334 abstract "Dinitrosyl nonheme-iron complexes can appear in cells and tissues overproducing nitric oxide. It is believed that due to their chemical nature these species may be implicated in certain pathophysiological events. We studied the possible role of low molecular mass dinitrosyl iron complexes in the control of noradrenaline release in electrically stimulated rat tail artery.A model complex, dinitrosyl-iron-thiosulfate (at 1-10 microM) produced a concentration-dependent enhancement of electrical field stimulated [3H]noradrenaline release (up to 2 fold). At the same time, dinitrosyl-iron-thiosulfate inhibited neurogenic vasoconstriction, consistent with its nitric oxide donor properties. A specific inhibitor of cyclic GMP dependent protein kinase, Rp-8pCPT-cGMPS, partially inhibited the effect of dinitrosyl-iron-thiosulfate on neurogenic vasoconstriction, but not on [3H]noradrenaline release. Another model complex, dinitrosyl-iron-cysteine (at 3 microM) elicited similar responses as dinitrosyl-iron-thiosulfate. Conventional NO and NO+ donors such as sodium nitroprusside, S-nitroso-L-cysteine or S-nitroso-glutathione (at 10 microM) had no effect on [3H]noradrenaline release, though they potently decreased electrically-induced vasoconstriction. The false complex, iron(II)-thiosulfate showed no activity.Low molecular mass iron dinitrosyl complexes can up-regulate the stimulation-evoked release of vascular [3H]noradrenaline, apparently independently of their NO donor properties. This finding may have important implications in inflammatory tissues." @default.
• W1552015334 created "2016-06-24" @default.
• W1552015334 creator A5027320385 @default.
• W1552015334 creator A5035254382 @default.
• W1552015334 creator A5079129742 @default.
• W1552015334 creator A5084001156 @default.
• W1552015334 creator A5090687556 @default.
• W1552015334 date "2002-01-01" @default.
• W1552015334 modified "2023-09-30" @default.
• W1552015334 cites W1580076592 @default.
• W1552015334 cites W1718691538 @default.
• W1552015334 cites W1970721812 @default.
• W1552015334 cites W1970893153 @default.
• W1552015334 cites W1977448081 @default.
• W1552015334 cites W1987165240 @default.
• W1552015334 cites W2006211213 @default.
• W1552015334 cites W2006984835 @default.
• W1552015334 cites W2009843075 @default.
• W1552015334 cites W2012796994 @default.
• W1552015334 cites W2013030279 @default.
• W1552015334 cites W2014194922 @default.
• W1552015334 cites W2022595505 @default.
• W1552015334 cites W2025072007 @default.
• W1552015334 cites W2049863374 @default.
• W1552015334 cites W2064058819 @default.
• W1552015334 cites W2064061480 @default.
• W1552015334 cites W2069093131 @default.
• W1552015334 cites W2073429475 @default.
• W1552015334 cites W2074212602 @default.
• W1552015334 cites W2102015901 @default.
• W1552015334 cites W2172212573 @default.
• W1552015334 cites W2179702494 @default.
• W1552015334 cites W2190335352 @default.
• W1552015334 cites W2275261188 @default.
• W1552015334 cites W2328371733 @default.
• W1552015334 doi "https://doi.org/10.1186/1471-2210-2-3" @default.
• W1552015334 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/65697" @default.
• W1552015334 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11872148" @default.
• W1552015334 hasPublicationYear "2002" @default.
• W1552015334 type Work @default.
• W1552015334 sameAs 1552015334 @default.
• W1552015334 citedByCount "7" @default.
• W1552015334 crossrefType "journal-article" @default.
• W1552015334 hasAuthorship W1552015334A5027320385 @default.
• W1552015334 hasAuthorship W1552015334A5035254382 @default.
• W1552015334 hasAuthorship W1552015334A5079129742 @default.
• W1552015334 hasAuthorship W1552015334A5084001156 @default.
• W1552015334 hasAuthorship W1552015334A5090687556 @default.
• W1552015334 hasBestOaLocation W15520153341 @default.
• W1552015334 hasConcept C120770815 @default.
• W1552015334 hasConcept C134018914 @default.
• W1552015334 hasConcept C178790620 @default.
• W1552015334 hasConcept C181199279 @default.
• W1552015334 hasConcept C185592680 @default.
• W1552015334 hasConcept C2776015013 @default.
• W1552015334 hasConcept C2779201268 @default.
• W1552015334 hasConcept C2779610285 @default.
• W1552015334 hasConcept C2779961880 @default.
• W1552015334 hasConcept C2781090017 @default.
• W1552015334 hasConcept C518881349 @default.
• W1552015334 hasConcept C519581460 @default.
• W1552015334 hasConcept C538909803 @default.
• W1552015334 hasConcept C55493867 @default.
• W1552015334 hasConcept C86803240 @default.
• W1552015334 hasConcept C98274493 @default.
• W1552015334 hasConceptScore W1552015334C120770815 @default.
• W1552015334 hasConceptScore W1552015334C134018914 @default.
• W1552015334 hasConceptScore W1552015334C178790620 @default.
• W1552015334 hasConceptScore W1552015334C181199279 @default.
• W1552015334 hasConceptScore W1552015334C185592680 @default.
• W1552015334 hasConceptScore W1552015334C2776015013 @default.
• W1552015334 hasConceptScore W1552015334C2779201268 @default.
• W1552015334 hasConceptScore W1552015334C2779610285 @default.
• W1552015334 hasConceptScore W1552015334C2779961880 @default.
• W1552015334 hasConceptScore W1552015334C2781090017 @default.
• W1552015334 hasConceptScore W1552015334C518881349 @default.
• W1552015334 hasConceptScore W1552015334C519581460 @default.
• W1552015334 hasConceptScore W1552015334C538909803 @default.
• W1552015334 hasConceptScore W1552015334C55493867 @default.
• W1552015334 hasConceptScore W1552015334C86803240 @default.
• W1552015334 hasConceptScore W1552015334C98274493 @default.
• W1552015334 hasIssue "1" @default.
• W1552015334 hasLocation W15520153341 @default.
• W1552015334 hasLocation W15520153342 @default.
• W1552015334 hasLocation W15520153343 @default.
• W1552015334 hasLocation W15520153344 @default.
• W1552015334 hasOpenAccess W1552015334 @default.
• W1552015334 hasPrimaryLocation W15520153341 @default.
• W1552015334 hasRelatedWork W1552015334 @default.
• W1552015334 hasRelatedWork W1974610845 @default.
• W1552015334 hasRelatedWork W2029984904 @default.
• W1552015334 hasRelatedWork W2132019871 @default.
• W1552015334 hasRelatedWork W2987945590 @default.
• W1552015334 hasRelatedWork W3149295483 @default.
• W1552015334 hasRelatedWork W4302774236 @default.
• W1552015334 hasRelatedWork W8756730 @default.
• W1552015334 hasRelatedWork W2019224933 @default.
• W1552015334 hasRelatedWork W2442452542 @default.

• next