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- W1552092088 abstract "The hemagglutinin subunits of two strains of avian influenza virus isolated from ducks in 1972 and 1973 were shown to cross react with the hemagglutinin subunits of the Asian 1957 strain of human influenza virus in hemagglutination-inhibition and immunodiffusion tests. The duck and human viruses possessed “common” and “specific” antigenic determinants on their hemagglutinin (HA) subunits. The duck viruses, which differed in neuraminidase antigens, were designated A/duck/GDR/72 (H2 Nav?) and A/duck/1215/73 (H2 Nav2). Peptide maps of the polypeptide chains (HA1 and HA2) from the hemagglutinin subunits of Asian/57 influenza virus and the duck/Germany/1215/73 strain showed similarities suggesting that some similar amino acid sequences occurred in the HA subunits of the avian and human viruses. On the strength of these results, we postulate a group of avian influenza viruses with hemagglutinin subunits related to those of the 1957 Asian influenza virus and possibly also to those of the virus that caused the influenza epidemic in 1889. In each case one of these avian viruses may have served as the donor of the hemagglutinin subunits for the formation of the human pandemic influenza strain." @default.
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- W1552092088 date "1975-10-01" @default.
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- W1552092088 title "Studies on the origin of pandemic influenza viruses" @default.
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- W1552092088 doi "https://doi.org/10.1016/0042-6822(75)90453-5" @default.
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