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- W1552159568 abstract "This chapter describes the molecular pathology ones performed to characterize the function of Raf kinase inhibitor protein (RKIP) in prostate cancer carcinoma. Particularly, the immunohistochemistry (IHC) technology used to validate our observations in clinical setting are discussed. The role of RKIP in diagnostic and prognostic application is also discussed. Prostate cancer is a multifactorial disease with genetic and environmental components involved in its etiology. It is characterized by heterogeneous growth patterns that range from slow-growing tumors to very rapid-growing, highly metastatic tumors. The heterogeneity of prostate cancer makes it difficult to define genetic markers for this disease. Standard therapy relies on removing or blocking the action of androgens. In most cases, this therapy results in a regression of the cancer. However, a portion of the cancer eventually relapses and metastasizes to other organs." @default.
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- W1552159568 date "2002-01-01" @default.
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- W1552159568 title "20 Immunohistochemical expression of raf kinase inhibitor protein in prostate carcinoma" @default.
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- W1552159568 doi "https://doi.org/10.1016/s1874-5784(02)80052-6" @default.
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