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• W1552176566 abstract "Reduced expression of the mitochondrial protein Frataxin (FXN) is the underlying cause of Friedreich's ataxia. We propose a model of premature termination of FXN transcription induced by pathogenic expanded GAA repeats that links R-loop structures, antisense transcription, and heterochromatin formation as a novel mechanism of transcriptional repression in Friedreich's ataxia." @default.
• W1552176566 created "2016-06-24" @default.
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• W1552176566 date "2015-03-15" @default.
• W1552176566 modified "2023-09-27" @default.
• W1552176566 title "Friedreich's ataxia – a case of aberrant transcription termination?" @default.
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• W1552176566 doi "https://doi.org/10.1080/21541264.2015.1026538" @default.
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