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- W1552614411 abstract "In vivo voltammetry was performed in rat brain cortex and in rat brain endothelial constitutive NO-synthase preparations. The use of a recent microcaptor detecting N-hydroxy- and N-nitroso-l-arginine permitted to find only the latest in biological preparations. The construction of a new membrane selective electrode for nitric oxide (NO) allowed to assert its absence in these preparations at micromolar level. Half-live of N-nitroso-l-arginine was 4 s in rat brain cortex and the washout curve of NO after over brain insufflation gave an half-life of 10.5 min; their diffusion coefficients in brain were 3.810−2 for NO and 3.910−6 cm2 · s−1 for N-nitroso-l-arginine. These facts indicate that N-nitroso-l-arginine is degraded directly into nitrites and citrulline after its synthesis by endothelial NO-synthase." @default.
- W1552614411 created "2016-06-24" @default.
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- W1552614411 date "1994-04-01" @default.
- W1552614411 modified "2023-10-02" @default.
- W1552614411 title "Diffusion coefficients and half-lives of nitric oxide and in rat cortex" @default.
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- W1552614411 doi "https://doi.org/10.1016/0304-3940(94)90612-2" @default.
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