Matches in SemOpenAlex for { <https://semopenalex.org/work/W1553288155> ?p ?o ?g. }
- W1553288155 endingPage "246" @default.
- W1553288155 startingPage "235" @default.
- W1553288155 abstract "The ecto-5'-nucleotidase from the cattle tick Boophilus microplus is an unusual enzyme, hydrolysing a variety of nucleoside mono-, di- and triphosphates to release the free nucleoside. The gene has been sequenced and the recombinant protein expressed as a functional, active enzyme. Nevertheless, the function of the enzyme in the tick remains obscure. The enzyme is present throughout the life cycle, but in largest amounts in unfed larvae and adult ticks. The tissue location has been studied in adult female ticks by Western blotting, RT-PCR and immunofluorescence. All methods show the enzyme to be principally in the Malpighian tubules, though significant amounts are also present on the surface of ovaries and in detectable amounts in other tissues. This, together with the known specificity of the enzyme, suggests a role in purine salvage pathways. Sensitivity of ticks to allopurinol, an inhibitor of hypoxanthine-guanine-phosphoribosyltransferase, supports the importance of purine salvage in this tick and the potential role of nucleotidase in this pathway." @default.
- W1553288155 created "2016-06-24" @default.
- W1553288155 creator A5014920600 @default.
- W1553288155 creator A5047159619 @default.
- W1553288155 creator A5054738613 @default.
- W1553288155 creator A5060718309 @default.
- W1553288155 creator A5066250216 @default.
- W1553288155 date "2000-01-01" @default.
- W1553288155 modified "2023-10-09" @default.
- W1553288155 cites W135039810 @default.
- W1553288155 cites W1552811851 @default.
- W1553288155 cites W1965903586 @default.
- W1553288155 cites W1969091586 @default.
- W1553288155 cites W1994016728 @default.
- W1553288155 cites W2003217869 @default.
- W1553288155 cites W2018289835 @default.
- W1553288155 cites W2043809434 @default.
- W1553288155 cites W2045218977 @default.
- W1553288155 cites W2054083589 @default.
- W1553288155 cites W2065347324 @default.
- W1553288155 cites W2072023619 @default.
- W1553288155 cites W2073171765 @default.
- W1553288155 cites W2076193826 @default.
- W1553288155 cites W2076817223 @default.
- W1553288155 cites W2077646727 @default.
- W1553288155 cites W2094566712 @default.
- W1553288155 cites W2099804835 @default.
- W1553288155 cites W2100837269 @default.
- W1553288155 cites W2101108802 @default.
- W1553288155 cites W2103223904 @default.
- W1553288155 cites W2108342610 @default.
- W1553288155 cites W2460275605 @default.
- W1553288155 doi "https://doi.org/10.1023/a:1006452325210" @default.
- W1553288155 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11108389" @default.
- W1553288155 hasPublicationYear "2000" @default.
- W1553288155 type Work @default.
- W1553288155 sameAs 1553288155 @default.
- W1553288155 citedByCount "15" @default.
- W1553288155 countsByYear W15532881552016 @default.
- W1553288155 countsByYear W15532881552017 @default.
- W1553288155 countsByYear W15532881552022 @default.
- W1553288155 countsByYear W15532881552023 @default.
- W1553288155 crossrefType "journal-article" @default.
- W1553288155 hasAuthorship W1553288155A5014920600 @default.
- W1553288155 hasAuthorship W1553288155A5047159619 @default.
- W1553288155 hasAuthorship W1553288155A5054738613 @default.
- W1553288155 hasAuthorship W1553288155A5060718309 @default.
- W1553288155 hasAuthorship W1553288155A5066250216 @default.
- W1553288155 hasConcept C104317684 @default.
- W1553288155 hasConcept C150149183 @default.
- W1553288155 hasConcept C153911025 @default.
- W1553288155 hasConcept C173758957 @default.
- W1553288155 hasConcept C181199279 @default.
- W1553288155 hasConcept C18880352 @default.
- W1553288155 hasConcept C194101687 @default.
- W1553288155 hasConcept C22145727 @default.
- W1553288155 hasConcept C2776476023 @default.
- W1553288155 hasConcept C2776543447 @default.
- W1553288155 hasConcept C2777913276 @default.
- W1553288155 hasConcept C2777995097 @default.
- W1553288155 hasConcept C28212737 @default.
- W1553288155 hasConcept C2992994097 @default.
- W1553288155 hasConcept C512185932 @default.
- W1553288155 hasConcept C55493867 @default.
- W1553288155 hasConcept C59822182 @default.
- W1553288155 hasConcept C86803240 @default.
- W1553288155 hasConcept C90856448 @default.
- W1553288155 hasConceptScore W1553288155C104317684 @default.
- W1553288155 hasConceptScore W1553288155C150149183 @default.
- W1553288155 hasConceptScore W1553288155C153911025 @default.
- W1553288155 hasConceptScore W1553288155C173758957 @default.
- W1553288155 hasConceptScore W1553288155C181199279 @default.
- W1553288155 hasConceptScore W1553288155C18880352 @default.
- W1553288155 hasConceptScore W1553288155C194101687 @default.
- W1553288155 hasConceptScore W1553288155C22145727 @default.
- W1553288155 hasConceptScore W1553288155C2776476023 @default.
- W1553288155 hasConceptScore W1553288155C2776543447 @default.
- W1553288155 hasConceptScore W1553288155C2777913276 @default.
- W1553288155 hasConceptScore W1553288155C2777995097 @default.
- W1553288155 hasConceptScore W1553288155C28212737 @default.
- W1553288155 hasConceptScore W1553288155C2992994097 @default.
- W1553288155 hasConceptScore W1553288155C512185932 @default.
- W1553288155 hasConceptScore W1553288155C55493867 @default.
- W1553288155 hasConceptScore W1553288155C59822182 @default.
- W1553288155 hasConceptScore W1553288155C86803240 @default.
- W1553288155 hasConceptScore W1553288155C90856448 @default.
- W1553288155 hasIssue "3" @default.
- W1553288155 hasLocation W15532881551 @default.
- W1553288155 hasLocation W15532881552 @default.
- W1553288155 hasOpenAccess W1553288155 @default.
- W1553288155 hasPrimaryLocation W15532881551 @default.
- W1553288155 hasRelatedWork W1526553691 @default.
- W1553288155 hasRelatedWork W1553288155 @default.
- W1553288155 hasRelatedWork W2028732522 @default.
- W1553288155 hasRelatedWork W2065320472 @default.
- W1553288155 hasRelatedWork W2076817223 @default.
- W1553288155 hasRelatedWork W2086038894 @default.
- W1553288155 hasRelatedWork W2103223904 @default.