Matches in SemOpenAlex for { <https://semopenalex.org/work/W155365800> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W155365800 endingPage "6" @default.
- W155365800 startingPage "451" @default.
- W155365800 abstract "There are three phases of acute hemorrhagic shock after trauma. In phase I (from injury to operation for control of bleeding) the patient suffers from low cardiac output, tachycardia, reduced organ perfusion, oliguria and decreased capillary hydrostatic pressure, which in turn reduces extravascular fluid loss. Contraction of the interstitial space matrix replenishes plasma volume. Optimal therapy includes blood and crystalloid replacement to restore plasma volume, red cell mass and interstitial fluid. Three litres of crystalloid are usually required for each litre of blood lost. After operation, a period of obligatory extravascular fluid sequestration occurs as the intracellular and interstitial spaces expand (phase II). Optimal replacement therapy during this phase maintains plasma volume. Replacement is provided according to the patient's vital signs, because extravascular fluid expansion cannot be influenced by therapeutic manipulation. Phase III is a mobilization and diuretic phase. During this phase systolic hypertension may occur, and the patient must be treated with restriction of fluid, diuresis and careful monitoring of the heart and lungs. Attempts to alter these physiologic responses with supplemental albumin have proved detrimental. The albumin causes salt and water retention in the nephron, leading to weight gain, higher central filing pressures and worsening pulmonary function, and a greater need for diuretic and inotropic therapy. Albumin therapy also induces relocation of non-albumin proteins into the interstitial space, leading to impaired immunocompetence and coagulation. Successful resuscitation is facilitated by adaptation to these physiologic responses of hemorrhagic shock rather than manipulation of them." @default.
- W155365800 created "2016-06-24" @default.
- W155365800 creator A5076343166 @default.
- W155365800 date "1990-12-01" @default.
- W155365800 modified "2023-09-23" @default.
- W155365800 title "Update on trauma care in Canada. 4. Resuscitation through the three phases of hemorrhagic shock after trauma." @default.
- W155365800 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2253121" @default.
- W155365800 hasPublicationYear "1990" @default.
- W155365800 type Work @default.
- W155365800 sameAs 155365800 @default.
- W155365800 citedByCount "3" @default.
- W155365800 countsByYear W1553658002014 @default.
- W155365800 crossrefType "journal-article" @default.
- W155365800 hasAuthorship W155365800A5076343166 @default.
- W155365800 hasConcept C126322002 @default.
- W155365800 hasConcept C164705383 @default.
- W155365800 hasConcept C2776125364 @default.
- W155365800 hasConcept C2777808716 @default.
- W155365800 hasConcept C2778165595 @default.
- W155365800 hasConcept C2780283014 @default.
- W155365800 hasConcept C2781300812 @default.
- W155365800 hasConcept C2781309813 @default.
- W155365800 hasConcept C37557685 @default.
- W155365800 hasConcept C42219234 @default.
- W155365800 hasConcept C71924100 @default.
- W155365800 hasConceptScore W155365800C126322002 @default.
- W155365800 hasConceptScore W155365800C164705383 @default.
- W155365800 hasConceptScore W155365800C2776125364 @default.
- W155365800 hasConceptScore W155365800C2777808716 @default.
- W155365800 hasConceptScore W155365800C2778165595 @default.
- W155365800 hasConceptScore W155365800C2780283014 @default.
- W155365800 hasConceptScore W155365800C2781300812 @default.
- W155365800 hasConceptScore W155365800C2781309813 @default.
- W155365800 hasConceptScore W155365800C37557685 @default.
- W155365800 hasConceptScore W155365800C42219234 @default.
- W155365800 hasConceptScore W155365800C71924100 @default.
- W155365800 hasIssue "6" @default.
- W155365800 hasLocation W1553658001 @default.
- W155365800 hasOpenAccess W155365800 @default.
- W155365800 hasPrimaryLocation W1553658001 @default.
- W155365800 hasRelatedWork W1979539209 @default.
- W155365800 hasRelatedWork W2059257341 @default.
- W155365800 hasRelatedWork W2069476908 @default.
- W155365800 hasRelatedWork W2081059115 @default.
- W155365800 hasRelatedWork W2090700290 @default.
- W155365800 hasRelatedWork W2097033056 @default.
- W155365800 hasRelatedWork W2911617010 @default.
- W155365800 hasRelatedWork W3024762409 @default.
- W155365800 hasRelatedWork W33978341 @default.
- W155365800 hasRelatedWork W4290689098 @default.
- W155365800 hasVolume "33" @default.
- W155365800 isParatext "false" @default.
- W155365800 isRetracted "false" @default.
- W155365800 magId "155365800" @default.
- W155365800 workType "article" @default.