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• W1553811453 abstract "Primary esophageal melanoma is a rare malignant entity. Ithas been estimated that since its first description in 1964, nomore than 300 cases have been described in the internationalliterature. It represents only 0.1% of all malignant esophagealneoplasms. Amelanotic melanomas represent a minorityof all esophageal melanomas. The aim of this presentationis to describe the diagnostic and therapeutic manipulationsapplied in a patient with amelanotic primary esophagealmelanoma. Case report: A man aged 65, was admitted toour department because of dysphagia in solid foods of twomonths duration. Physical examination revealed nothingimportant. He was a non-smoker and he denied alcohol consumption.Upper GI barium follow-through showed a feelingdefect in the lower third of the esophagus without significantprestenotic dilatation. Upper GI endoscopy revealedthe presence of a neoplasm, occupying almost the entire lumenof the esophagus, in an area of at least 5cm. Nevertheless,passing the endoscope through the stenotic lumen ofthe esophagus could easily be achieved. Histology of tumorsamples, revealed the presence of malignant amelanotic esophagealmelanoma. Immunohistochemical study showedthat the malignant cells were negative in panceratine, ceratine7 and AE3 (epithelial indices) and positive to VimentinS100, HMB45 and MART1. Computed tomography of thewhole body showed a small metastatic lesion in the liver, withoutlymph-node involvement. Skin examination revealed nothingimportant. Ophthalmological examination was negative.Chemotherapy consisting of Cisplatin 90mg/m2 IV (1st day)and Temodal 150mg/m2 tb po (1st and 5th day), every 25 days(3 cycles) combined with radiotherapy were applied. Fourmonths later satellite lesions in the esophagus, and lung andliver metastases were found. Palliation treatment with Interferon-a, was unsuccessful. After one month Fotemustine wasgiven with little improvement. The patient died after 3 moremonths. Conclusion: Primary amelanotic esophageal melanomais a rare neoplasm with dismal prognosis. Modern histochemistrycan significantly facilitate the correct diagnosis.Key Words: Esophageal melanoma, Esophageal tumors,Malignant melanoma" @default.
• W1553811453 created "2016-06-24" @default.
• W1553811453 creator A5059292158 @default.
• W1553811453 creator A5070195130 @default.
• W1553811453 date "2007-09-04" @default.
• W1553811453 modified "2023-09-26" @default.
• W1553811453 title "Primary malignant esophageal melanoma: Diagnostic and therapeutic manipulations of a Greek patient and review of the literature" @default.
• W1553811453 cites W100104337 @default.
• W1553811453 cites W1537505931 @default.
• W1553811453 cites W160865004 @default.
• W1553811453 cites W1966320277 @default.
• W1553811453 cites W1976477657 @default.
• W1553811453 cites W1976486530 @default.
• W1553811453 cites W1978534792 @default.
• W1553811453 cites W1986648091 @default.
• W1553811453 cites W1987004978 @default.
• W1553811453 cites W1990222826 @default.
• W1553811453 cites W1993862197 @default.
• W1553811453 cites W1994401656 @default.
• W1553811453 cites W2017839140 @default.
• W1553811453 cites W2024600316 @default.
• W1553811453 cites W2024616022 @default.
• W1553811453 cites W2027406263 @default.
• W1553811453 cites W2027644778 @default.
• W1553811453 cites W2031747707 @default.
• W1553811453 cites W2031859392 @default.
• W1553811453 cites W2043450060 @default.
• W1553811453 cites W2044147508 @default.
• W1553811453 cites W2048087588 @default.
• W1553811453 cites W2049756708 @default.
• W1553811453 cites W2054520107 @default.
• W1553811453 cites W2060744023 @default.
• W1553811453 cites W2061101589 @default.
• W1553811453 cites W2062341928 @default.
• W1553811453 cites W2064504288 @default.
• W1553811453 cites W2067826072 @default.
• W1553811453 cites W2068504994 @default.
• W1553811453 cites W2068593224 @default.
• W1553811453 cites W2068728510 @default.
• W1553811453 cites W2075397423 @default.
• W1553811453 cites W2076076357 @default.
• W1553811453 cites W2079070152 @default.
• W1553811453 cites W2082136191 @default.
• W1553811453 cites W2084851474 @default.
• W1553811453 cites W2085496633 @default.
• W1553811453 cites W2086066720 @default.
• W1553811453 cites W2088085072 @default.
• W1553811453 cites W2088422488 @default.
• W1553811453 cites W2091521338 @default.
• W1553811453 cites W2094182512 @default.
• W1553811453 cites W2094304272 @default.
• W1553811453 cites W2112621446 @default.
• W1553811453 cites W2116698624 @default.
• W1553811453 cites W2127746314 @default.
• W1553811453 cites W2164221293 @default.
• W1553811453 cites W2167656468 @default.
• W1553811453 cites W2167807973 @default.
• W1553811453 cites W2282513120 @default.
• W1553811453 cites W2312628816 @default.
• W1553811453 cites W2322766723 @default.
• W1553811453 cites W2340803476 @default.
• W1553811453 cites W2346840717 @default.
• W1553811453 cites W2362158700 @default.
• W1553811453 cites W2395345808 @default.
• W1553811453 cites W2395868302 @default.
• W1553811453 cites W2396839782 @default.
• W1553811453 cites W2397488979 @default.
• W1553811453 cites W2399752884 @default.
• W1553811453 cites W2400510566 @default.
• W1553811453 cites W2402860357 @default.
• W1553811453 cites W2403515712 @default.
• W1553811453 cites W2405648002 @default.
• W1553811453 cites W2406540790 @default.
• W1553811453 cites W2406919085 @default.
• W1553811453 cites W2408878828 @default.
• W1553811453 cites W2409043667 @default.
• W1553811453 cites W2409494291 @default.
• W1553811453 cites W2409957403 @default.
• W1553811453 cites W2410533662 @default.
• W1553811453 cites W2410554360 @default.
• W1553811453 cites W2410836220 @default.
• W1553811453 cites W2411128328 @default.
• W1553811453 cites W2412668010 @default.
• W1553811453 cites W2413320192 @default.
• W1553811453 cites W2413935382 @default.
• W1553811453 cites W2414500153 @default.
• W1553811453 cites W2414524779 @default.
• W1553811453 cites W2414768647 @default.
• W1553811453 cites W2416126891 @default.
• W1553811453 cites W2416162951 @default.
• W1553811453 cites W2416596016 @default.
• W1553811453 cites W2416718569 @default.
• W1553811453 cites W2417199455 @default.
• W1553811453 cites W2418307455 @default.
• W1553811453 cites W2418315968 @default.
• W1553811453 cites W2418992183 @default.
• W1553811453 cites W2431166623 @default.
• W1553811453 cites W2432277994 @default.
• W1553811453 cites W2433435073 @default.
• W1553811453 cites W2435396480 @default.

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