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- W1554140717 abstract "Effect of acoustic nonlinearity of biological tissue results in ultrasound waveform distortion and, for high level of acoustic pressure, in formation of shock fronts. This effect may be strongly pronounced for high intensity focused ultrasound (HIFU). When the sawtooth waveform is developed at the focus, the corresponding absorption rate increases. This can be used in therapeutic applications of HIFU, such as focused surgery and hemostasis, when it is desirable to achieve localized elevated absorption. Nonlinear enhancement of heating is studied experimentally and theoretically in tissue phantom for 1.1 MHz piezoceramic sources of 10 cm diameter 20 cm focal length. Continuous ultrasound wave and repetitive tone bursts of the same mean power are employed to study the effect of the nonlinearity on temperature rise in gelatin. The experimental data are compared with the results of numerical modeling of the temperature field. The theory is based on the KZK-type equation for the acoustic field combined with the Bio-Heat equation for the temperature. A significant increase of temperature rise was predicted and observed for 1000 W/cm peak intensities due to the excess absorption at the shocks." @default.
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- W1554140717 date "2001-01-01" @default.
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- W1554140717 title "Thermal effects of sawtooth waveform HIFU in tissue phantoms" @default.
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