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- W1554325830 abstract "Abstract One hundred and sixteen patients with Stage I endometrial carcinoma were treated by hysterectomy with or without preoperative radiation therapy. Survival was slightly but not significantly increased in the group who received preoperative irradiation. The survival rates were identical when examination of the hysterectomy specimen showed no residual tumor or tumor limited to the endometrium after radiation, but survival was significantly poorer when myometrial extension was present. The incidence of complete tumor sterilization was considerably higher in uteri removed more than 5 weeks following the completion of radiation therapy. When residual tumor was present after radiation, its histologic characteristics were seldom altered from those observed in material obtained before treatment, and bizarre radiation changes were seen almost exclusively in benign endometrial glands. Our data indicate that carcinomas limited to the endometrium are frequently sterilized by preoperative radium but that survival is not changed appreciably in these cases. Tumors with myometrial extension, which have a poorer prognosis, appear to be considerably less frequently sterilized by the techniques employed in this series. Implications for therapy based on these histologic data are presented." @default.
- W1554325830 created "2016-06-24" @default.
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- W1554325830 date "1974-07-01" @default.
- W1554325830 modified "2023-09-27" @default.
- W1554325830 title "Histopathologic analysis of preoperative radiation therapy in endometrial carcinoma" @default.
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- W1554325830 doi "https://doi.org/10.1016/0002-9378(74)90135-5" @default.
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