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• W1554591720 abstract "Compared to the controls, activities of hepatic enzymes involved in fatty acid synthesis were decreased in rats ingesting orotic acid for 6 days or longer. In contrast, activities of these enzymes were markedly enhanced in adipose tissue. Fatty acid synthesis and 14CO2 production from glucose-U-14C were depressed in liver and stimulated in white or brown adipose tissue. The data obtained in an in vivo study follow a pattern similar to those observed with in vitro preparations. The results suggest that orotic acid increases fatty acid turnover in adipose tissue." @default.
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• W1554591720 date "1970-12-01" @default.
• W1554591720 modified "2023-10-02" @default.
• W1554591720 title "Dietary Orotic Acid and Lipogenesis in the Rat" @default.
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• W1554591720 doi "https://doi.org/10.1093/jn/100.12.1431" @default.
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