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- W1554647846 abstract "Introduction: The use of synbiotic in the management of constipation seems to be promising, particularly in patients with amyotrophic lateral sclerosis (ALS) which have constipation as a frequent symptom.Objective: To evaluate the effect of synbiotic supplementation on intestinal function of constipated patients with ALS. Materials and Methods: This interventional study was performed with ALS patients followed at the ALS multidisciplinary ambulatory of Hospital Universitário Onofre Lopes (HUOL) at the Federal University of Rio Grande do Norte (UFRN). Subjects were arranged in three groups: 10 healthy controls (group 1), 10 ALS constipated patients (group 2), and 10 ALS non-constipated patients (group 3). All subjects received synbiotic supplementation (6g/day) during 15 days and their intestinal function was monitored daily.Results: We studied 30 subjects (13 male and 17 female) with mean age 54.3 ± 10.6 years. Group 1 didn’t show major modifications in the parameters observed. Nevertheless, groups 2 and 3 improved the intestinal function, with increased frequency of bowel movements, improved stool consistency and less evacuation effort. These benefits were observed after one-week of synbiotic supplementation.Conclusion: Regular use of synbiotic can improve intestinal function in both constipated and non-constipated ALS patients." @default.
- W1554647846 created "2016-06-24" @default.
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- W1554647846 date "2013-12-19" @default.
- W1554647846 modified "2023-09-24" @default.
- W1554647846 title "Uso de simbiótico no tratamento de pacientes obstipados com esclerose lateral amiotrófica" @default.
- W1554647846 doi "https://doi.org/10.15448/1983-652x.2013.3.13548" @default.
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