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- W1555091497 abstract "Publisher SummaryThis chapter traces a brief history of human functional brain mapping. Functional brain imaging with positron emission tomography (PET) and magnetic resonance imaging is made possible because blood flow changes locally in the brain in relation to changes in cellular activity. Even though the blood flow response is delayed somewhat in time due to a sluggish response of blood vessels to changes in neuronal activity, it is remarkable how reliable it appears to be in reflecting changes in cellular activity in the normal brain. One of the critical aspects in the emergence of PET for quantitative in vivo autoradiography in humans was the ability of the developers of the technique to take full advantage of the image reconstruction technique of filtered backprojection. The typical reaction within the scientific and industrial community to the introduction of computed tomography (CT) was that far better image reconstruction algorithms could be developed for CT and better scanners built than the ones being offered by Electrical and Musical Industries, Limited. Work on the neural correlates of human behaviors with PET began with studies of brain glucose metabolism and the tracer 18F-2-fluoro-2-deoxy-D-glucose." @default.
- W1555091497 created "2016-06-24" @default.
- W1555091497 creator A5039215935 @default.
- W1555091497 date "2000-01-01" @default.
- W1555091497 modified "2023-10-03" @default.
- W1555091497 title "A Brief History of Human Functional Brain Mapping" @default.
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