Matches in SemOpenAlex for { <https://semopenalex.org/work/W1555700027> ?p ?o ?g. }
- W1555700027 abstract "Publisher Summary This chapter focuses on the hormonal and cell-specific regulation of human growth hormone (hGH) and chorionic somatomammotropin (hCS) gene. The pituitary hGH-1 and the placental hCS-1, hCS-2, and hGH-2 genes are unique in primates because they have evolved very recently and have maintained ∼95% nucleotide sequence identity. Consequently, they form a particularly interesting gene family for the study of cell-specific regulatory mechanisms and may represent an important set of genes that played a unique role in primate evolution. Both hCS and hGH-2 are found in the maternal circulation and their concentrations increase throughout pregnancy, reaching their respective maxima near term. CS appears to have both lactogenic and somatogenic effects. CS may not have a primary role in mammary development because individuals appear to have normal breast development and lactation in isolated deficiencies of CS, or GH, or prolactin. The control of GH gene expression by cyclic adenosine monophosphate in anterior pituitary somatotroph occurs through a cascade mechanism initiated primarily by the action of two antagonistic hypothalamic neurohormones: Somatostatin inhibits GH release and growth-hormone-releasing-hormone (GHRH) regulates both GH synthesis and secretion.." @default.
- W1555700027 created "2016-06-24" @default.
- W1555700027 creator A5010329918 @default.
- W1555700027 creator A5015930256 @default.
- W1555700027 creator A5037240694 @default.
- W1555700027 creator A5049232174 @default.
- W1555700027 creator A5072141013 @default.
- W1555700027 date "1996-01-01" @default.
- W1555700027 modified "2023-09-22" @default.
- W1555700027 title "Hormonal and Cell-specific Regulation of the Human Growth Hormone and Chorionic Somatomammotropin Genes" @default.
- W1555700027 cites W1270583954 @default.
- W1555700027 cites W1408783740 @default.
- W1555700027 cites W1450500198 @default.
- W1555700027 cites W1509665044 @default.
- W1555700027 cites W1513220089 @default.
- W1555700027 cites W1516518871 @default.
- W1555700027 cites W1520441844 @default.
- W1555700027 cites W1532344573 @default.
- W1555700027 cites W1532539575 @default.
- W1555700027 cites W1538576447 @default.
- W1555700027 cites W1552077171 @default.
- W1555700027 cites W1553675422 @default.
- W1555700027 cites W1555807734 @default.
- W1555700027 cites W1556768294 @default.
- W1555700027 cites W1559480198 @default.
- W1555700027 cites W1562551320 @default.
- W1555700027 cites W1562563314 @default.
- W1555700027 cites W1565293177 @default.
- W1555700027 cites W1577897019 @default.
- W1555700027 cites W1578555932 @default.
- W1555700027 cites W1580606703 @default.
- W1555700027 cites W1583056254 @default.
- W1555700027 cites W1583375627 @default.
- W1555700027 cites W1584074881 @default.
- W1555700027 cites W1600649289 @default.
- W1555700027 cites W1607529566 @default.
- W1555700027 cites W1790472336 @default.
- W1555700027 cites W1819829467 @default.
- W1555700027 cites W184563540 @default.
- W1555700027 cites W1850907373 @default.
- W1555700027 cites W1943482784 @default.
- W1555700027 cites W1947779414 @default.
- W1555700027 cites W1963066038 @default.
- W1555700027 cites W1963977413 @default.
- W1555700027 cites W1967533605 @default.
- W1555700027 cites W1967665887 @default.
- W1555700027 cites W1968039555 @default.
- W1555700027 cites W1970101500 @default.
- W1555700027 cites W1972988912 @default.
- W1555700027 cites W1974952841 @default.
- W1555700027 cites W1975776209 @default.
- W1555700027 cites W1976569357 @default.
- W1555700027 cites W1977281537 @default.
- W1555700027 cites W1979392504 @default.
- W1555700027 cites W1979698007 @default.
- W1555700027 cites W1985736574 @default.
- W1555700027 cites W1986644535 @default.
- W1555700027 cites W1987010524 @default.
- W1555700027 cites W1987553475 @default.
- W1555700027 cites W1987906273 @default.
- W1555700027 cites W1988256844 @default.
- W1555700027 cites W1995037787 @default.
- W1555700027 cites W1995340855 @default.
- W1555700027 cites W1998665089 @default.
- W1555700027 cites W1999270780 @default.
- W1555700027 cites W1999414596 @default.
- W1555700027 cites W2000324336 @default.
- W1555700027 cites W2000913970 @default.
- W1555700027 cites W2000987137 @default.
- W1555700027 cites W2001160272 @default.
- W1555700027 cites W2001794206 @default.
- W1555700027 cites W2003002984 @default.
- W1555700027 cites W2004002827 @default.
- W1555700027 cites W2005101151 @default.
- W1555700027 cites W2005297028 @default.
- W1555700027 cites W2005934192 @default.
- W1555700027 cites W2006408340 @default.
- W1555700027 cites W2007770553 @default.
- W1555700027 cites W2008570049 @default.
- W1555700027 cites W2010034236 @default.
- W1555700027 cites W2011679875 @default.
- W1555700027 cites W2017900917 @default.
- W1555700027 cites W2018213065 @default.
- W1555700027 cites W2018312073 @default.
- W1555700027 cites W2020017275 @default.
- W1555700027 cites W2022909974 @default.
- W1555700027 cites W2023872113 @default.
- W1555700027 cites W2023950569 @default.
- W1555700027 cites W2024725484 @default.
- W1555700027 cites W2025176530 @default.
- W1555700027 cites W2026230914 @default.
- W1555700027 cites W2026548183 @default.
- W1555700027 cites W2028193482 @default.
- W1555700027 cites W2028263033 @default.
- W1555700027 cites W2028285437 @default.
- W1555700027 cites W2028477931 @default.
- W1555700027 cites W2030904938 @default.
- W1555700027 cites W2030928772 @default.
- W1555700027 cites W2032318665 @default.
- W1555700027 cites W2032684131 @default.