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• W1555989815 abstract "<strong><span style=font-family: TimesNewRomanPS-BoldMT;><strong><span style=font-family: TimesNewRomanPS-BoldMT;><font face=TimesNewRomanPS-BoldMT><p align=left> </p></font></span><p align=left><span style=font-size: x-small; font-family: TimesNewRomanPS-BoldMT;><span style=font-size: x-small; font-family: TimesNewRomanPS-BoldMT;>ABSTRACT</span></span></p></strong><span style=font-size: x-small; font-family: TimesNewRomanPSMT;><span style=font-size: x-small; font-family: TimesNewRomanPSMT;><p align=left>Pharmacoepidemiology is defined as the the study of the use and the effects of drugs in large groups of</p><p align=left>people. It can be viewed as an epidemiological discipline with particular focus on drugs. The Scandinavians</p><p align=left>pioneered the developement of methods to study drug utilization. The ATC and DDD methodology is now a</p><p align=left>widely accepted consensus on how to categorise drugs and compare sales of drugs of different potency. The</p><p align=left>hierachy of available designs to study drug effects is described. There is an inverse relationship between the</p><p align=left>validity of a study design and its resource requirements. One of the most pervasive methodological problems</p><p align=left>of pharmacoepidemiology is the possibility of confounding by indication. Often, such confounding can only</p><p align=left>be handled by mounting a randomised trial. If a trial is unethical or unfeasible, the research question has the</p><p align=left>potential of becoming af standing controversy. The emergence of large population based prescription databases</p><p align=left>is an exciting new development in pharmacoepidemiology. The validity of drug exposure data is discussed.</p><p align=left>It is established that data from a pharmacy based database should be preferred over data from a GP</p><p align=left>based database. Whether interview data are preferable to dispensing data can not be established in general</p><p>but may occasionally be inferred from the context of the research question.</p></span></span></span></strong><strong><span style=font-size: x-small; font-family: TimesNewRomanPS-BoldMT;></span></strong>" @default.
• W1555989815 created "2016-06-24" @default.
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• W1555989815 date "2009-11-06" @default.
• W1555989815 modified "2023-10-02" @default.
• W1555989815 title "Pharmacoepidemiology – current opportunities and challenges" @default.
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• W1555989815 doi "https://doi.org/10.5324/nje.v11i1.527" @default.
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