FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1556296738> ?p ?o ?g. }

• W1556296738 abstract "Enzymes are deformable molecules which often adapt their conformation to the substrate’s geometry. In the case of restriction enzymes acting on DNA, the substrate (DNA) is deformable also. While it is well established that external mechanical stress exerted on an enzyme modulates the enzymatic activity, the effect of mechanically stressing the substrate is less explored. Here we present the restriction enzyme EcoRV with a series of pre-bent DNA substrates and observe modulation of the overall speed of the enzymatic reaction by up to a factor 50. While in all cases the reaction is slowed down compared to the unstressed substrate, we observe peaks in the reaction rate as we vary the state of stress of the DNA substrate. Both bending moments and torsional moments on the DNA substrate affect the reaction rate." @default.
• W1556296738 created "2016-06-24" @default.
• W1556296738 creator A5023039636 @default.
• W1556296738 creator A5085646546 @default.
• W1556296738 date "2015-05-01" @default.
• W1556296738 modified "2023-09-23" @default.
• W1556296738 title "EcoRV catalysis with a pre-bent substrate" @default.
• W1556296738 cites W1539904997 @default.
• W1556296738 cites W1619891693 @default.
• W1556296738 cites W1968079241 @default.
• W1556296738 cites W1969751133 @default.
• W1556296738 cites W1976428644 @default.
• W1556296738 cites W1978220321 @default.
• W1556296738 cites W1992474912 @default.
• W1556296738 cites W1996271437 @default.
• W1556296738 cites W2016910708 @default.
• W1556296738 cites W2025947376 @default.
• W1556296738 cites W2043317558 @default.
• W1556296738 cites W2050565744 @default.
• W1556296738 cites W2052039588 @default.
• W1556296738 cites W2052221476 @default.
• W1556296738 cites W2055992062 @default.
• W1556296738 cites W2056010224 @default.
• W1556296738 cites W2060199013 @default.
• W1556296738 cites W2062292011 @default.
• W1556296738 cites W2083354230 @default.
• W1556296738 cites W2086642544 @default.
• W1556296738 cites W2098208486 @default.
• W1556296738 cites W2108568179 @default.
• W1556296738 cites W2132315489 @default.
• W1556296738 cites W2150032924 @default.
• W1556296738 cites W2319705280 @default.
• W1556296738 cites W2324585399 @default.
• W1556296738 cites W2330750947 @default.
• W1556296738 cites W2332605850 @default.
• W1556296738 cites W4254085062 @default.
• W1556296738 cites W72251605 @default.
• W1556296738 doi "https://doi.org/10.1063/1.4921837" @default.
• W1556296738 hasPublicationYear "2015" @default.
• W1556296738 type Work @default.
• W1556296738 sameAs 1556296738 @default.
• W1556296738 citedByCount "3" @default.
• W1556296738 countsByYear W15562967382019 @default.
• W1556296738 countsByYear W15562967382020 @default.
• W1556296738 crossrefType "journal-article" @default.
• W1556296738 hasAuthorship W1556296738A5023039636 @default.
• W1556296738 hasAuthorship W1556296738A5085646546 @default.
• W1556296738 hasBestOaLocation W15562967381 @default.
• W1556296738 hasConcept C12554922 @default.
• W1556296738 hasConcept C128319531 @default.
• W1556296738 hasConcept C130123407 @default.
• W1556296738 hasConcept C138211643 @default.
• W1556296738 hasConcept C159985019 @default.
• W1556296738 hasConcept C161790260 @default.
• W1556296738 hasConcept C178790620 @default.
• W1556296738 hasConcept C181199279 @default.
• W1556296738 hasConcept C185592680 @default.
• W1556296738 hasConcept C18903297 @default.
• W1556296738 hasConcept C192562407 @default.
• W1556296738 hasConcept C2776777567 @default.
• W1556296738 hasConcept C2777289219 @default.
• W1556296738 hasConcept C552990157 @default.
• W1556296738 hasConcept C55493867 @default.
• W1556296738 hasConcept C71240020 @default.
• W1556296738 hasConcept C8010536 @default.
• W1556296738 hasConcept C86803240 @default.
• W1556296738 hasConcept C87210426 @default.
• W1556296738 hasConceptScore W1556296738C12554922 @default.
• W1556296738 hasConceptScore W1556296738C128319531 @default.
• W1556296738 hasConceptScore W1556296738C130123407 @default.
• W1556296738 hasConceptScore W1556296738C138211643 @default.
• W1556296738 hasConceptScore W1556296738C159985019 @default.
• W1556296738 hasConceptScore W1556296738C161790260 @default.
• W1556296738 hasConceptScore W1556296738C178790620 @default.
• W1556296738 hasConceptScore W1556296738C181199279 @default.
• W1556296738 hasConceptScore W1556296738C185592680 @default.
• W1556296738 hasConceptScore W1556296738C18903297 @default.
• W1556296738 hasConceptScore W1556296738C192562407 @default.
• W1556296738 hasConceptScore W1556296738C2776777567 @default.
• W1556296738 hasConceptScore W1556296738C2777289219 @default.
• W1556296738 hasConceptScore W1556296738C552990157 @default.
• W1556296738 hasConceptScore W1556296738C55493867 @default.
• W1556296738 hasConceptScore W1556296738C71240020 @default.
• W1556296738 hasConceptScore W1556296738C8010536 @default.
• W1556296738 hasConceptScore W1556296738C86803240 @default.
• W1556296738 hasConceptScore W1556296738C87210426 @default.
• W1556296738 hasIssue "5" @default.
• W1556296738 hasLocation W15562967381 @default.
• W1556296738 hasOpenAccess W1556296738 @default.
• W1556296738 hasPrimaryLocation W15562967381 @default.
• W1556296738 hasRelatedWork W1509109125 @default.
• W1556296738 hasRelatedWork W1539904997 @default.
• W1556296738 hasRelatedWork W1556296738 @default.
• W1556296738 hasRelatedWork W2006869216 @default.
• W1556296738 hasRelatedWork W2016495866 @default.
• W1556296738 hasRelatedWork W2038816407 @default.
• W1556296738 hasRelatedWork W2057113828 @default.
• W1556296738 hasRelatedWork W2312681405 @default.
• W1556296738 hasRelatedWork W2807289865 @default.
• W1556296738 hasRelatedWork W2899084033 @default.

• next