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- W1556447985 abstract "Abnormal structure and function in the striatum and prefrontal cortex (PFC) have been revealed in Internet addiction disorder (IAD). However, little is known about alterations of corticostriatal functional circuits in IAD. The aim of this study was to investigate the integrity of corticostriatal functional circuits and their relations to neuropsychological measures in IAD by resting-state functional connectivity (FC). Fourteen IAD adolescents and 15 healthy controls underwent resting-state fMRI scans. Using six predefined bilateral striatal regions-of-interest, voxel-wise correlation maps were computed and compared between groups. Relationships between alterations of corticostriatal connectivity and clinical measurements were examined in the IAD group. Compared to controls, IAD subjects exhibited reduced connectivity between the inferior ventral striatum and bilateral caudate head, subgenual anterior cingulate cortex (ACC), and posterior cingulate cortex, and between the superior ventral striatum and bilateral dorsal/rostral ACC, ventral anterior thalamus, and putamen/pallidum/insula/inferior frontal gyrus (IFG), and between the dorsal caudate and dorsal/rostral ACC, thalamus, and IFG, and between the left ventral rostral putamen and right IFG. IAD subjects also showed increased connectivity between the left dorsal caudal putamen and bilateral caudal cigulate motor area. Moreover, altered cotricostriatal functional circuits were significantly correlated with neuropsychological measures. This study directly provides evidence that IAD is associated with alterations of corticostriatal functional circuits involved in the affective and motivation processing, and cognitive control. These findings emphasize that functional connections in the corticostriatal circuits are modulated by affective/motivational/cognitive states and further suggest that IAD may have abnormalities of such modulation in this network." @default.
- W1556447985 created "2016-06-24" @default.
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- W1556447985 date "2015-06-16" @default.
- W1556447985 modified "2023-09-26" @default.
- W1556447985 title "Aberrant corticostriatal functional circuits in adolescents with Internet addiction disorder" @default.
- W1556447985 cites W1513908461 @default.
- W1556447985 cites W1710601904 @default.
- W1556447985 cites W1720114320 @default.
- W1556447985 cites W1748789401 @default.
- W1556447985 cites W1914669721 @default.
- W1556447985 cites W1965970403 @default.
- W1556447985 cites W1970452940 @default.
- W1556447985 cites W1979777714 @default.
- W1556447985 cites W1981378299 @default.
- W1556447985 cites W1981725931 @default.
- W1556447985 cites W1982251878 @default.
- W1556447985 cites W1985715468 @default.
- W1556447985 cites W1986350274 @default.
- W1556447985 cites W1987464027 @default.
- W1556447985 cites W1989789686 @default.
- W1556447985 cites W1995372173 @default.
- W1556447985 cites W1998954528 @default.
- W1556447985 cites W2000753657 @default.
- W1556447985 cites W2008098183 @default.
- W1556447985 cites W2010382717 @default.
- W1556447985 cites W2012090015 @default.
- W1556447985 cites W2012440798 @default.
- W1556447985 cites W2012801579 @default.
- W1556447985 cites W2016237857 @default.
- W1556447985 cites W2019465558 @default.
- W1556447985 cites W2020407144 @default.
- W1556447985 cites W2025802167 @default.
- W1556447985 cites W2025848547 @default.
- W1556447985 cites W2029223431 @default.
- W1556447985 cites W2030055333 @default.
- W1556447985 cites W2030854448 @default.
- W1556447985 cites W2031139171 @default.
- W1556447985 cites W2032996762 @default.
- W1556447985 cites W2033765091 @default.
- W1556447985 cites W2034250255 @default.
- W1556447985 cites W2039534437 @default.
- W1556447985 cites W2042133749 @default.
- W1556447985 cites W2044740696 @default.
- W1556447985 cites W2045800887 @default.
- W1556447985 cites W2050964630 @default.
- W1556447985 cites W2054515032 @default.
- W1556447985 cites W2059312295 @default.
- W1556447985 cites W2060321692 @default.
- W1556447985 cites W2061978884 @default.
- W1556447985 cites W2065953611 @default.
- W1556447985 cites W2066916484 @default.
- W1556447985 cites W2067456724 @default.
- W1556447985 cites W2069691347 @default.
- W1556447985 cites W2072001523 @default.
- W1556447985 cites W2076683771 @default.
- W1556447985 cites W2077292484 @default.
- W1556447985 cites W2077416121 @default.
- W1556447985 cites W2077823633 @default.
- W1556447985 cites W2078530990 @default.
- W1556447985 cites W2082014247 @default.
- W1556447985 cites W2083415528 @default.
- W1556447985 cites W2084699651 @default.
- W1556447985 cites W2086766205 @default.
- W1556447985 cites W2087495858 @default.
- W1556447985 cites W2088631924 @default.
- W1556447985 cites W2089996056 @default.
- W1556447985 cites W2091605579 @default.
- W1556447985 cites W2095438393 @default.
- W1556447985 cites W2097405825 @default.
- W1556447985 cites W2099527308 @default.
- W1556447985 cites W2099652807 @default.
- W1556447985 cites W2105337517 @default.
- W1556447985 cites W2108891761 @default.
- W1556447985 cites W2117085868 @default.
- W1556447985 cites W2119285123 @default.
- W1556447985 cites W2124358336 @default.
- W1556447985 cites W2125823313 @default.
- W1556447985 cites W2129404974 @default.
- W1556447985 cites W2129624700 @default.
- W1556447985 cites W2134128653 @default.
- W1556447985 cites W2140798832 @default.
- W1556447985 cites W2142160213 @default.
- W1556447985 cites W2144538553 @default.
- W1556447985 cites W2144802702 @default.
- W1556447985 cites W2150364599 @default.
- W1556447985 cites W2150857753 @default.
- W1556447985 cites W2159569422 @default.
- W1556447985 cites W2163133925 @default.
- W1556447985 cites W2167834909 @default.
- W1556447985 cites W2168628650 @default.
- W1556447985 cites W4254909614 @default.
- W1556447985 doi "https://doi.org/10.3389/fnhum.2015.00356" @default.
- W1556447985 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4468611" @default.