FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1556526714> ?p ?o ?g. }

• W1556526714 endingPage "1298" @default.
• W1556526714 startingPage "1287" @default.
• W1556526714 abstract "Summary Expression of the gene pcnB , encoding the dispensable Escherichia coli poly(A) polymerase (PAPI), which is toxic when overproduced, was investigated. Its promoter was identified and found to be moderately strong when used to express a β‐galactosidase reporter. Expression levels were not affected by increasing or decreasing PcnB concentration. Translation of pcnB was found to initiate from the non‐canonical initiation codon AUU. The only other coli gene reported to use AUU as initiation codon is infC , which encodes the initiation factor IF‐3. AUU, in common with other rarely used initiation codons, is discriminated against by IF‐3, resulting in the aborting of most AUU‐promoted initiation events. This enables AUU to form part of an autoregulatory circuit controlling IF‐3 production. We show that InfC discrimination reduces PcnB production fivefold. This is the first instance of this mechanism being used to limit severely the production of a potentially toxic product." @default.
• W1556526714 created "2016-06-24" @default.
• W1556526714 creator A5006218427 @default.
• W1556526714 creator A5062470293 @default.
• W1556526714 date "2002-05-23" @default.
• W1556526714 modified "2023-10-18" @default.
• W1556526714 title "Expression of the Escherichia coli pcnB gene is translationally limited using an inefficient start codon: a second chromosomal example of translation initiated at AUU" @default.
• W1556526714 cites W140176686 @default.
• W1556526714 cites W1525643420 @default.
• W1556526714 cites W1529139551 @default.
• W1556526714 cites W1982468347 @default.
• W1556526714 cites W1990520494 @default.
• W1556526714 cites W1992042701 @default.
• W1556526714 cites W1993128416 @default.
• W1556526714 cites W2002958448 @default.
• W1556526714 cites W2012344563 @default.
• W1556526714 cites W2014252739 @default.
• W1556526714 cites W2019807330 @default.
• W1556526714 cites W2019979853 @default.
• W1556526714 cites W2020887690 @default.
• W1556526714 cites W203277925 @default.
• W1556526714 cites W2036931150 @default.
• W1556526714 cites W2043246656 @default.
• W1556526714 cites W2051449352 @default.
• W1556526714 cites W2064374186 @default.
• W1556526714 cites W2065295874 @default.
• W1556526714 cites W206825036 @default.
• W1556526714 cites W2078368201 @default.
• W1556526714 cites W2079254989 @default.
• W1556526714 cites W2082051303 @default.
• W1556526714 cites W2085211780 @default.
• W1556526714 cites W2091434091 @default.
• W1556526714 cites W2092098631 @default.
• W1556526714 cites W2102428326 @default.
• W1556526714 cites W210765743 @default.
• W1556526714 cites W2112130400 @default.
• W1556526714 cites W2128031437 @default.
• W1556526714 cites W2129561341 @default.
• W1556526714 cites W2131045262 @default.
• W1556526714 cites W2134153749 @default.
• W1556526714 cites W2134660959 @default.
• W1556526714 cites W2135444969 @default.
• W1556526714 cites W2141653906 @default.
• W1556526714 cites W2142731338 @default.
• W1556526714 cites W2158752325 @default.
• W1556526714 cites W2160183974 @default.
• W1556526714 cites W4296765338 @default.
• W1556526714 doi "https://doi.org/10.1046/j.1365-2958.2002.02945.x" @default.
• W1556526714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12068810" @default.
• W1556526714 hasPublicationYear "2002" @default.
• W1556526714 type Work @default.
• W1556526714 sameAs 1556526714 @default.
• W1556526714 citedByCount "50" @default.
• W1556526714 countsByYear W15565267142012 @default.
• W1556526714 countsByYear W15565267142014 @default.
• W1556526714 countsByYear W15565267142015 @default.
• W1556526714 countsByYear W15565267142016 @default.
• W1556526714 countsByYear W15565267142017 @default.
• W1556526714 countsByYear W15565267142018 @default.
• W1556526714 countsByYear W15565267142019 @default.
• W1556526714 countsByYear W15565267142020 @default.
• W1556526714 countsByYear W15565267142021 @default.
• W1556526714 countsByYear W15565267142022 @default.
• W1556526714 crossrefType "journal-article" @default.
• W1556526714 hasAuthorship W1556526714A5006218427 @default.
• W1556526714 hasAuthorship W1556526714A5062470293 @default.
• W1556526714 hasBestOaLocation W15565267141 @default.
• W1556526714 hasConcept C104317684 @default.
• W1556526714 hasConcept C105580179 @default.
• W1556526714 hasConcept C141231307 @default.
• W1556526714 hasConcept C149364088 @default.
• W1556526714 hasConcept C153911025 @default.
• W1556526714 hasConcept C176990463 @default.
• W1556526714 hasConcept C20580545 @default.
• W1556526714 hasConcept C3675279 @default.
• W1556526714 hasConcept C4718897 @default.
• W1556526714 hasConcept C54355233 @default.
• W1556526714 hasConcept C547475151 @default.
• W1556526714 hasConcept C86803240 @default.
• W1556526714 hasConcept C87253356 @default.
• W1556526714 hasConceptScore W1556526714C104317684 @default.
• W1556526714 hasConceptScore W1556526714C105580179 @default.
• W1556526714 hasConceptScore W1556526714C141231307 @default.
• W1556526714 hasConceptScore W1556526714C149364088 @default.
• W1556526714 hasConceptScore W1556526714C153911025 @default.
• W1556526714 hasConceptScore W1556526714C176990463 @default.
• W1556526714 hasConceptScore W1556526714C20580545 @default.
• W1556526714 hasConceptScore W1556526714C3675279 @default.
• W1556526714 hasConceptScore W1556526714C4718897 @default.
• W1556526714 hasConceptScore W1556526714C54355233 @default.
• W1556526714 hasConceptScore W1556526714C547475151 @default.
• W1556526714 hasConceptScore W1556526714C86803240 @default.
• W1556526714 hasConceptScore W1556526714C87253356 @default.
• W1556526714 hasIssue "5" @default.
• W1556526714 hasLocation W15565267141 @default.
• W1556526714 hasLocation W15565267142 @default.
• W1556526714 hasOpenAccess W1556526714 @default.
• W1556526714 hasPrimaryLocation W15565267141 @default.

• next