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• W1556609966 endingPage "149" @default.
• W1556609966 startingPage "138" @default.
• W1556609966 abstract "T-cell development primarily occurs in the thymus and involves in the interactions of many important transcription factors. Until recently, no single transcription factor has been identified to be essential for T-cell lineage commitment or maintenance of T-cell identity. Recent studies have now identified the zinc finger transcription factor Bcl11b to be essential for T-cell development and for maintenance of T-cell identity. Remarkably, T cells acquire NK cell properties upon Bcl11b deletion. These reprogrammed cells have unique properties in proliferation, cytokine dependency and killing target cells, and may therefore provide a new cell source for some cell-based therapies." @default.
• W1556609966 created "2016-06-24" @default.
• W1556609966 creator A5015985377 @default.
• W1556609966 creator A5071458554 @default.
• W1556609966 creator A5073407618 @default.
• W1556609966 date "2010-10-25" @default.
• W1556609966 modified "2023-10-16" @default.
• W1556609966 title "Critical roles of Bcl11b in T-cell development and maintenance of T-cell identity" @default.
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