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• W1556627846 abstract "The induction of beta-interferon is markedly enhanced in some cell types by a pretreatment with type I interferon itself (priming). We show that induction in response to double-stranded RNA is completely dependent upon priming in HeLa cells. However, unprimed cells can be partially induced by Sendai virus. This indicates that Sendai virus can provide a signal that is different from, or additional to, that provided by double-stranded RNA. The requirement for priming cannot be localized to a specific sequence element in the beta-interferon promoter, suggesting that priming may induce an essential component for signal transduction in response to double-stranded RNA." @default.
• W1556627846 created "2016-06-24" @default.
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• W1556627846 date "1994-12-01" @default.
• W1556627846 modified "2023-10-14" @default.
• W1556627846 title "The beta-interferon promoter responds to priming through multiple independent regulatory elements." @default.
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• W1556627846 doi "https://doi.org/10.1016/s0021-9258(18)43857-4" @default.
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