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- W1556687169 abstract "Key Points Tumor IDO inhibits CD19-CART activity, likely via induction of the kynurenine pathway, whose metabolites directly inhibit T cells. Fludarabine and cyclophosphamide, frequently used before CART administration, downregulate IDO expression in lymphoma cells." @default.
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- W1556687169 date "2015-06-18" @default.
- W1556687169 modified "2023-10-14" @default.
- W1556687169 title "Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs" @default.
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- W1556687169 doi "https://doi.org/10.1182/blood-2015-01-621474" @default.
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