Matches in SemOpenAlex for { <https://semopenalex.org/work/W1557020811> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1557020811 abstract "In previous reports, we have identified cell-surface glycopeptides from mouse cerebrum (BCSG) that inhibited protein synthesis and mitosis in several cell types. When baby hamster kidney (BHK)-21 cells were infected with vesicular stomatitis virus (a negative strand RNA virus), BCSG extensively inhibited viral protein synthesis. This inhibition was effective against both protein and glycoprotein synthesis and was independent of amino acid uptake by infected cells, synthesis of viral RNA, and degradation of viral proteins. Analysis of polyribosome profiles in uninfected BHK-21 cells indicated that the degree of cellular protein synthesis inhibition could not be attributed to activation of RNase or solely to a disruption of chain initiation. When added directly to a cell-free protein-synthesizing system derived from BHK-21 cells, BCSG was ineffective, but if the inhibitory material was first allowed to react with cells, cell-free protein synthesis was substantially reduced. When BCSG were reacted with cells for 5 min at 0 degrees C, the cells tested, BHK-21 (a BCSG-sensitive line) and murine fibrosarcoma 2237 (a BCSG-insensitive line), both effectively adsorbed the inhibitor from the medium." @default.
- W1557020811 created "2016-06-24" @default.
- W1557020811 creator A5020019863 @default.
- W1557020811 creator A5088687918 @default.
- W1557020811 creator A5090468019 @default.
- W1557020811 date "1980-08-01" @default.
- W1557020811 modified "2023-09-28" @default.
- W1557020811 title "Glycopeptides from brain inhibit rates of polypeptide chain elongation." @default.
- W1557020811 cites W1545162664 @default.
- W1557020811 cites W1587199142 @default.
- W1557020811 cites W1883537315 @default.
- W1557020811 cites W1890351154 @default.
- W1557020811 cites W1927706448 @default.
- W1557020811 cites W1964323580 @default.
- W1557020811 cites W1964504520 @default.
- W1557020811 cites W1964784148 @default.
- W1557020811 cites W1969375788 @default.
- W1557020811 cites W1977251643 @default.
- W1557020811 cites W1981229103 @default.
- W1557020811 cites W1983126873 @default.
- W1557020811 cites W1991119501 @default.
- W1557020811 cites W2002846971 @default.
- W1557020811 cites W2014335282 @default.
- W1557020811 cites W2041193908 @default.
- W1557020811 cites W2073762409 @default.
- W1557020811 cites W2085521084 @default.
- W1557020811 cites W2094879489 @default.
- W1557020811 cites W2100837269 @default.
- W1557020811 cites W2126200877 @default.
- W1557020811 cites W21687688 @default.
- W1557020811 doi "https://doi.org/10.1016/s0021-9258(18)43746-5" @default.
- W1557020811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6248520" @default.
- W1557020811 hasPublicationYear "1980" @default.
- W1557020811 type Work @default.
- W1557020811 sameAs 1557020811 @default.
- W1557020811 citedByCount "10" @default.
- W1557020811 crossrefType "journal-article" @default.
- W1557020811 hasAuthorship W1557020811A5020019863 @default.
- W1557020811 hasAuthorship W1557020811A5088687918 @default.
- W1557020811 hasAuthorship W1557020811A5090468019 @default.
- W1557020811 hasBestOaLocation W15570208111 @default.
- W1557020811 hasConcept C104317684 @default.
- W1557020811 hasConcept C108625454 @default.
- W1557020811 hasConcept C1491633281 @default.
- W1557020811 hasConcept C153911025 @default.
- W1557020811 hasConcept C185592680 @default.
- W1557020811 hasConcept C2778128677 @default.
- W1557020811 hasConcept C2779200571 @default.
- W1557020811 hasConcept C33263850 @default.
- W1557020811 hasConcept C3675279 @default.
- W1557020811 hasConcept C54355233 @default.
- W1557020811 hasConcept C55493867 @default.
- W1557020811 hasConcept C65666806 @default.
- W1557020811 hasConcept C67705224 @default.
- W1557020811 hasConcept C81885089 @default.
- W1557020811 hasConcept C86803240 @default.
- W1557020811 hasConcept C88478588 @default.
- W1557020811 hasConceptScore W1557020811C104317684 @default.
- W1557020811 hasConceptScore W1557020811C108625454 @default.
- W1557020811 hasConceptScore W1557020811C1491633281 @default.
- W1557020811 hasConceptScore W1557020811C153911025 @default.
- W1557020811 hasConceptScore W1557020811C185592680 @default.
- W1557020811 hasConceptScore W1557020811C2778128677 @default.
- W1557020811 hasConceptScore W1557020811C2779200571 @default.
- W1557020811 hasConceptScore W1557020811C33263850 @default.
- W1557020811 hasConceptScore W1557020811C3675279 @default.
- W1557020811 hasConceptScore W1557020811C54355233 @default.
- W1557020811 hasConceptScore W1557020811C55493867 @default.
- W1557020811 hasConceptScore W1557020811C65666806 @default.
- W1557020811 hasConceptScore W1557020811C67705224 @default.
- W1557020811 hasConceptScore W1557020811C81885089 @default.
- W1557020811 hasConceptScore W1557020811C86803240 @default.
- W1557020811 hasConceptScore W1557020811C88478588 @default.
- W1557020811 hasLocation W15570208111 @default.
- W1557020811 hasOpenAccess W1557020811 @default.
- W1557020811 hasPrimaryLocation W15570208111 @default.
- W1557020811 hasRelatedWork W1492741326 @default.
- W1557020811 hasRelatedWork W1494585322 @default.
- W1557020811 hasRelatedWork W1542368139 @default.
- W1557020811 hasRelatedWork W1739123218 @default.
- W1557020811 hasRelatedWork W1812951185 @default.
- W1557020811 hasRelatedWork W1968345770 @default.
- W1557020811 hasRelatedWork W1969375788 @default.
- W1557020811 hasRelatedWork W1984899173 @default.
- W1557020811 hasRelatedWork W2007310891 @default.
- W1557020811 hasRelatedWork W2009563713 @default.
- W1557020811 hasRelatedWork W2018834339 @default.
- W1557020811 hasRelatedWork W2034097367 @default.
- W1557020811 hasRelatedWork W2035642748 @default.
- W1557020811 hasRelatedWork W2048769679 @default.
- W1557020811 hasRelatedWork W2050515874 @default.
- W1557020811 hasRelatedWork W2065593465 @default.
- W1557020811 hasRelatedWork W2069675476 @default.
- W1557020811 hasRelatedWork W2072747716 @default.
- W1557020811 hasRelatedWork W2326627785 @default.
- W1557020811 hasRelatedWork W2412373637 @default.
- W1557020811 isParatext "false" @default.
- W1557020811 isRetracted "false" @default.
- W1557020811 magId "1557020811" @default.
- W1557020811 workType "article" @default.