FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1557218655> ?p ?o ?g. }

• W1557218655 endingPage "1126" @default.
• W1557218655 startingPage "1111" @default.
• W1557218655 abstract "Summary Enteropathogenic Escherichia coli (EPEC) are a major cause of infant morbidity and mortality due to diarrhoea in developing countries. The pathogenesis of EPEC is dependent on a coordinated multi‐step process culminating in the intimate adherence of the organisms to the host's intestinal mucosa. During the initial stages of the EPEC colonization process, the fimbrial adhesin, bundle‐forming pili (BFP), plays an integral role. We previously reported that the major BFP structural subunit, bundlin, displays lectin‐like properties, which enables BFP to initially tether EPEC to N ‐acetyllactosamine (LacNAc) glycan receptors on host cell surfaces. We also reported that incubating EPEC with synthetic LacNAc‐bearing neoglycoconjugates not only inhibits their adherence to host cells, but also induces BFP retraction and subsequent degradation of the bundlin subunits. Herein, we demonstrate that the periplasmic serine protease, DegP, is required for degrading bundlin during this process. We also show that DegP appears to act as a bundlin chaperone during BFP assembly and that LacNAc‐BSA‐induced BFP retraction is followed by transcriptional upregulation of the BFP operon and downregulation of the locus of enterocyte effacement operons in EPEC." @default.
• W1557218655 created "2016-06-24" @default.
• W1557218655 creator A5028268383 @default.
• W1557218655 creator A5033893131 @default.
• W1557218655 creator A5040743258 @default.
• W1557218655 creator A5043577617 @default.
• W1557218655 creator A5045669808 @default.
• W1557218655 creator A5045921478 @default.
• W1557218655 creator A5062563213 @default.
• W1557218655 creator A5089121517 @default.
• W1557218655 creator A5090630233 @default.
• W1557218655 date "2010-05-21" @default.
• W1557218655 modified "2023-10-16" @default.
• W1557218655 title "N-acetyllactosamine-induced retraction of bundle-forming pili regulates virulence-associated gene expression in enteropathogenic Escherichia coli" @default.
• W1557218655 cites W1571328418 @default.
• W1557218655 cites W1701180156 @default.
• W1557218655 cites W1852806268 @default.
• W1557218655 cites W1942719252 @default.
• W1557218655 cites W1966072209 @default.
• W1557218655 cites W1980607288 @default.
• W1557218655 cites W1981209045 @default.
• W1557218655 cites W1988665513 @default.
• W1557218655 cites W2000083619 @default.
• W1557218655 cites W2009709891 @default.
• W1557218655 cites W2009714082 @default.
• W1557218655 cites W2011581454 @default.
• W1557218655 cites W2016613716 @default.
• W1557218655 cites W2021369351 @default.
• W1557218655 cites W2028981314 @default.
• W1557218655 cites W2036469496 @default.
• W1557218655 cites W2043580912 @default.
• W1557218655 cites W2067250734 @default.
• W1557218655 cites W2074520299 @default.
• W1557218655 cites W2076905975 @default.
• W1557218655 cites W2092621064 @default.
• W1557218655 cites W2092934126 @default.
• W1557218655 cites W2097190398 @default.
• W1557218655 cites W2107543672 @default.
• W1557218655 cites W2111719241 @default.
• W1557218655 cites W2112698132 @default.
• W1557218655 cites W2115826538 @default.
• W1557218655 cites W2117734751 @default.
• W1557218655 cites W2126577904 @default.
• W1557218655 cites W2126653706 @default.
• W1557218655 cites W2127920700 @default.
• W1557218655 cites W2130952141 @default.
• W1557218655 cites W2131159435 @default.
• W1557218655 cites W2134190531 @default.
• W1557218655 cites W2137314066 @default.
• W1557218655 cites W2144629404 @default.
• W1557218655 cites W2153545618 @default.
• W1557218655 cites W2163893130 @default.
• W1557218655 cites W2399312458 @default.
• W1557218655 doi "https://doi.org/10.1111/j.1365-2958.2010.07192.x" @default.
• W1557218655 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2900475" @default.
• W1557218655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20487271" @default.
• W1557218655 hasPublicationYear "2010" @default.
• W1557218655 type Work @default.
• W1557218655 sameAs 1557218655 @default.
• W1557218655 citedByCount "30" @default.
• W1557218655 countsByYear W15572186552012 @default.
• W1557218655 countsByYear W15572186552013 @default.
• W1557218655 countsByYear W15572186552014 @default.
• W1557218655 countsByYear W15572186552015 @default.
• W1557218655 countsByYear W15572186552016 @default.
• W1557218655 countsByYear W15572186552017 @default.
• W1557218655 countsByYear W15572186552018 @default.
• W1557218655 countsByYear W15572186552019 @default.
• W1557218655 countsByYear W15572186552022 @default.
• W1557218655 countsByYear W15572186552023 @default.
• W1557218655 crossrefType "journal-article" @default.
• W1557218655 hasAuthorship W1557218655A5028268383 @default.
• W1557218655 hasAuthorship W1557218655A5033893131 @default.
• W1557218655 hasAuthorship W1557218655A5040743258 @default.
• W1557218655 hasAuthorship W1557218655A5043577617 @default.
• W1557218655 hasAuthorship W1557218655A5045669808 @default.
• W1557218655 hasAuthorship W1557218655A5045921478 @default.
• W1557218655 hasAuthorship W1557218655A5062563213 @default.
• W1557218655 hasAuthorship W1557218655A5089121517 @default.
• W1557218655 hasAuthorship W1557218655A5090630233 @default.
• W1557218655 hasBestOaLocation W15572186551 @default.
• W1557218655 hasConcept C104317684 @default.
• W1557218655 hasConcept C127561419 @default.
• W1557218655 hasConcept C142724271 @default.
• W1557218655 hasConcept C174832134 @default.
• W1557218655 hasConcept C179470777 @default.
• W1557218655 hasConcept C201663137 @default.
• W1557218655 hasConcept C203075996 @default.
• W1557218655 hasConcept C2775962898 @default.
• W1557218655 hasConcept C2910478007 @default.
• W1557218655 hasConcept C2910768159 @default.
• W1557218655 hasConcept C54355233 @default.
• W1557218655 hasConcept C547475151 @default.
• W1557218655 hasConcept C60987743 @default.
• W1557218655 hasConcept C71924100 @default.
• W1557218655 hasConcept C86803240 @default.
• W1557218655 hasConcept C89423630 @default.
• W1557218655 hasConcept C95444343 @default.

• next