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- W1557239790 abstract "The overall purpose of the current thesis was to evaluate the influence of various exercise strategies on Parkinson's disease (PD). While countless exercise interventions have been investigated in PD, results have been weak and inconclusive at best. As such, there are currently no scientifically-validated recommendations for an optimal exercise intervention. The four studies comprising this thesis have attempted to address the shortcomings of previous literature, namely, inconsistent use of outcome measures, lack of PD symptomatic measures, varying lengths of exercise interventions, absence of a non-exercise control group, continued assessment of participants after exercise has ended, and verifying replicability of findings. The first study was focused on identifying objective outcome measures that are predictive or reflective of the classic symptoms associated with PD. Symptomatic assessment was conducted using the Unified Parkinson's disease Rating Scale (UPDRS), the current gold standard for assessment of PD symptom severity. Objective outcome measures included the timed-up-and-go (TUG), grooved pegboard (GP), and spatiotemporal aspects of self-paced gait (velocity, step length). Backward elimination regression analysis demonstrated that the place phase of the GP was the most predictive of UPDRS score. Interestingly, no objective outcome measures were strongly correlated with change on the symptomatic subsets that they were believed to be theoretically evaluating. The results point to the continued need to identify objective outcome measures reflective of symptomatic assessment. Further, exercise rehabilitation trials should combine outcome measures with symptomatic assessment to ensure that improvements are reflective of symptomatic improvement." @default.
- W1557239790 created "2016-06-24" @default.
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- W1557239790 date "2008-01-01" @default.
- W1557239790 modified "2023-09-26" @default.
- W1557239790 title "Evaluation of the Effects of Various Exercise Interventions on Parkinson’s Disease" @default.
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