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• W1557532744 abstract "The chemical kinetic equations for a simple metabolic scheme have been solved in general terms. The scheme is one which may be regarded as an approximate representation of a number of interesting metabolic situations. The special forms of the solution which result from several common sets of experimental conditions have been studied in detail. Some approximate solutions to the foregoing system, used by various authors for the isotopic study of protein turnover, have been examined and the validity of the approximations considered. The problem of growth induction—whether it is due to increased rate of synthesis or decreased rate of catabolism—has been considered in the light of the equations, and the possibilities for settling the question in terms of data on isotope incorporation have been discussed. The problem of the heterogeneity of metabolic pools within the organism has been discussed at length, and some proposals for a more, rigorous experimental analysis have been formulated." @default.
• W1557532744 created "2016-06-24" @default.
• W1557532744 creator A5058300426 @default.
• W1557532744 date "1953-09-01" @default.
• W1557532744 modified "2023-09-27" @default.
• W1557532744 title "The study of metabolic turnover rates by means of isotopic tracers" @default.
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• W1557532744 doi "https://doi.org/10.1016/0003-9861(53)90171-4" @default.
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